Feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients undergoing chemotherapy
Feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients undergoing chemotherapy
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DOI：
10.1007/s00520-003-0504-2
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发表时间：
2003-11-01
影响因子：
3.1
通讯作者：
Knutsen, L
中科院分区：
文献类型：
--
作者：
Adamsen, L;Midtgaard, J;Knutsen, L
癌症患者在诊断和治疗疾病时经常会经历相当大的体能和总体健康损失。本研究的目的是评估多维运动计划对正在接受辅助或大剂量化疗的晚期癌症患者的可行性、体能和健康益处。监督计划包括高强度和低强度的活动（体育锻炼，放松，按摩和身体意识训练）。共有23例患者，年龄在18至65岁之间（中位年龄为40岁），每组7至9例患者，每周9小时，持续6周。在项目完成前后，比较了重复最大值（RM）和最大摄氧量（VO（2）max）、体力活动水平和心理社会健康（EORTC QLQ-C30、SF-36、HAD）方面的体能。该方案是安全的，耐受性良好。完成率为85.2%。体能（1 RM，VO（2）max）和身体活动水平的提高非常显着增加。生活质量和总体福祉评估表明，在几个方面有所改善，但没有达到显著性。它的结论是，运动计划，结合高强度和低强度的身体活动，可用于预防和/或尽量减少身体不活动，疲劳，肌肉萎缩和能量损失的癌症患者接受化疗。
Cancer patients frequently experience considerable loss of physical capacity and general wellbeing when diagnosed and treated for their disease. The aim of this study was to evaluate the feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients during advanced stages of disease who are undergoing adjuvant or high-dose chemotherapy. The supervised program included high- and low-intensity activities (physical exercise, relaxation, massage, and body-awareness training). A total of 23 patients between 18 and 65 years of age (median 40 years) participated in groups of seven to nine patients for 9 h weekly for 6 weeks. Physical capacity in terms of repetition maximum (RM) and maximal oxygen uptake (VO(2)max), physical activity level and psychosocial wellbeing (EORTC QLQ-C30, SF-36, HAD) were compared prior to and after completion of the program. The program was safe and well tolerated. The completion rate was 85.2%. Highly significant increases in physical capacity (1RM, VO(2)max) and an improved level of physical activity were achieved. Quality of life and general wellbeing assessments indicated improvements in several measures, but without reaching significance. It is concluded that an exercise program, which combines high- and low-intensity physical activities, may be used to prevent and/or minimize physical inactivity, fatigue, muscle wasting and energy loss in cancer patients undergoing chemotherapy.