Hydroxysteroid Sulfotransferase SULT2B1b Promotes Hepatocellular Carcinoma Cells Proliferation In Vitro and In Vivo

Hydroxysteroid Sulfotransferase SULT2B1b Promotes Hepatocellular Carcinoma Cells Proliferation In Vitro and In Vivo
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羟基类固醇磺基转移酶 SULT2B1b 促进肝细胞癌细胞体外和体内增殖

DOI:
10.1371/journal.pone.0060853
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发表时间:
2013-04
期刊:
影响因子:
3.7
通讯作者:
Xiaobo Li
Xiaobo Li
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Yanxia Ning;Xiuling Zhi;Lianhua Yin;Xiaobo Li

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羟基类固醇磺基转移酶2B 1b(SULT 2B 1b)对3β-羟基类固醇的硫酸基团加成具有高度选择性。尽管先前的报道表明SULT 2B 1 b与肝细胞增殖相关,但这种关系更好地解释了SULT 2B 1 b与肝细胞增殖的关系。
Hydroxysteroid sulfotransferase 2B1b (SULT2B1b) is highly selective for the addition of sulfate groups to 3β-hydroxysteroids. Although previous reports have suggested that SULT2B1b is correlated with cell proliferation of hepatocytes, the relationship bet
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