Herbal medicines that benefit epidermal permeability barrier function
Herbal medicines that benefit epidermal permeability barrier function
复制标题
有益于表皮渗透屏障功能的草药
DOI：
10.1016/j.dsi.2015.04.009
复制
发表时间：
2015-06-01
影响因子：
2.5
通讯作者：
Man, Mao-Qiang
中科院分区：
文献类型：
--
作者：
Hu, Lizhi;Man, Huibin;Man, Mao-Qiang
Epidermal permeability barrier function plays a critical role in regulating cutaneous functions. Hence, researchers have been searching for effective and affordable regimens to enhance epidermal permeability barrier function. In addition to topical stratum corneum lipids, peroxisome proliferator-activated receptor, and liver X receptor ligands, herbal medicines have been proven to benefit epidermal permeability barrier function in both normal and diseased skin, including atopic dermatitis, glucocorticoid-induced skin damage, and UVB-damaged skin. The potential mechanisms by which herbal medicines improve the permeability barrier include stimulation of epidermal differentiation, lipid production, antimicrobial peptide expression, and antioxidation. Therefore, utilization of herbal medicines could be a valuable alternative approach to enhance epidermal permeability barrier function in order to prevent and/or treat skin disorders associated with permeability barrier abnormalities. Copyright (C) 2015, Taiwanese Dermatological Association. Published by Elsevier Taiwan LLC. All rights reserved.
