Maternal race and intergenerational preterm birth recurrence
Maternal race and intergenerational preterm birth recurrence
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DOI：
10.1016/j.ajog.2017.05.051
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发表时间：
2017-10-01
影响因子：
9.8
通讯作者：
Manuck, Tracy A.
中科院分区：
文献类型：
--
作者：
Smid, Marcela C.;Lee, Jong Hyung;Manuck, Tracy A.
背景：早产是一种复杂的疾病，具有遗传性遗传成分。对早产的主要是白色妇女的研究表明，她们随后早产的风险增加。这种代际早产的风险是不好的定义在黑人women.OBJECTIVE：我们的目的是评估和比较代际早产的风险之间的非西班牙裔黑人和非西班牙裔白色mothers.Study设计：这是一个以人口为基础的回顾性队列研究，使用弗吉尼亚州代际关联出生档案。纳入了1960年至1996年出生于弗吉尼亚州的所有非西班牙裔黑人和非西班牙裔白色母亲，这些母亲在2005年至2009年期间分娩了第一个活产、非异常、单胎婴儿>= 20周。我们评估了足月和早产的非西班牙裔黑人和白色母亲的总体胎龄分布（
BACKGROUND: Preterm birth is a complex disorder with a heritable genetic component. Studies of primarily White women born preterm show that they have an increased risk of subsequently delivering preterm. This risk of intergenerational preterm birth is poorly defined among Black women.OBJECTIVE: Our objective was to evaluate and compare intergenerational preterm birth risk among non-Hispanic Black and non-Hispanic White mothers.STUDY DESIGN: This was a population-based retrospective cohort study, using the Virginia Intergenerational Linked Birth File. All nonHispanic Black and non-Hispanic White mothers born in Virginia 1960 through 1996 who delivered their first live-born, nonanomalous, singleton infant >= 20 weeks from 2005 through 2009 were included. We assessed the overall gestational age distribution between nonHispanic Black and White mothers born term and preterm (