The Centre of the Brain: Topographical Model of Motor, Cognitive, Affective, and Somatosensory Functions of the Basal Ganglia
The Centre of the Brain: Topographical Model of Motor, Cognitive, Affective, and Somatosensory Functions of the Basal Ganglia
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DOI：
10.1002/hbm.22124
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发表时间：
2013-11-01
影响因子：
4.8
通讯作者：
Taylor, Margot J.
中科院分区：
文献类型：
--
作者：
Arsalidou, Marie;Duerden, Emma G.;Taylor, Margot J.
基底神经节传统上被视为运动处理核团;然而，功能性神经影像学证据表明这些结构参与了更复杂的认知和情感过程，这些过程对一系列人类活动至关重要。使用定量荟萃分析方法，我们评估了健康参与者的基底神经节核团与运动（身体和眼球运动），认知（工作记忆和执行），情感（情绪和奖励）和体感功能相关的功能分区。我们的文件中的尾状头的前部与左半球内的最重叠的情感过程。认知过程表现出最广泛的反应，而运动过程占据更多的中央结构。在基底神经节的这些功能作用的基础上，我们提供了一个新的全面的地形模型，这些核团和洞察它们是如何与广泛的行为。《脑地图》34：3031-3054，2013年。(c)2012年威利期刊公司
The basal ganglia have traditionally been viewed as motor processing nuclei; however, functional neuroimaging evidence has implicated these structures in more complex cognitive and affective processes that are fundamental for a range of human activities. Using quantitative meta-analysis methods we assessed the functional subdivisions of basal ganglia nuclei in relation to motor (body and eye movements), cognitive (working-memory and executive), affective (emotion and reward) and somatosensory functions in healthy participants. We document affective processes in the anterior parts of the caudate head with the most overlap within the left hemisphere. Cognitive processes showed the most widespread response, whereas motor processes occupied more central structures. On the basis of these demonstrated functional roles of the basal ganglia, we provide a new comprehensive topographical model of these nuclei and insight into how they are linked to a wide range of behaviors. Hum Brain Mapp 34:3031-3054, 2013. (c) 2012 Wiley Periodicals, Inc.