Enantioselective Hydrative para‐ Dearomatization of Sulfonanilides by an Indanol‐based Chiral Organoiodine Catalyst
Enantioselective Hydrative para‐ Dearomatization of Sulfonanilides by an Indanol‐based Chiral Organoiodine Catalyst
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DOI：
10.1002/ajoc.202100152
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发表时间：
2021-04
影响因子：
2.7
通讯作者：
Yuto Shimazaki;Chisato Wata;T. Hashimoto;K. Maruoka
中科院分区：
文献类型：
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作者：
Yuto Shimazaki;Chisato Wata;T. Hashimoto;K. Maruoka
我们在此报告了通过使用基于茚满醇的手性有机碘催化剂，最初在我们的小组中开发的磺酰苯胺与水的对映选择性氧化帕拉脱芳构化的开发。通过使用N-甲磺酰基保护的苯胺作为底物，该反应有效地进行，以良好的产率和中等至高的对映选择性得到官能化的对苯二酚亚胺。
We report herein the development of an enantioselective oxidative para‐dearomatization of sulfonanilides with water by use of an indanol‐based chiral organoiodine catalyst, originally developed in our group. This reaction proceeds efficiently by the use of N‐mesyl‐protected anilines as substrates, giving functionalized p‐quinol imines in good yields and moderate to high enantioselectivities.