FAT AND CARBOHYDRATE OVERFEEDING IN HUMANS - DIFFERENT EFFECTS ON ENERGY-STORAGE
FAT AND CARBOHYDRATE OVERFEEDING IN HUMANS - DIFFERENT EFFECTS ON ENERGY-STORAGE
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DOI：
10.1093/ajcn/62.1.19
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发表时间：
1995-07-01
影响因子：
7.1
通讯作者：
HILL, JO
中科院分区：
文献类型：
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作者：
HORTON, TJ;DROUGAS, H;HILL, JO
食物的数量和成分都会影响体重调节。本研究的目的是确定是否以及通过何种机制过量的膳食脂肪导致更大的脂肪积累比过量的膳食碳水化合物。我们给9名瘦男性和7名肥胖男性过量喂食等能量的脂肪和碳水化合物（各14天）（超过能量需求的50%）。一个全房间的热量计被用来测量能量消耗和营养氧化的O，1，7，和14天的每个过度喂养期。根据能量和营养平衡（摄入-支出），我们估计了储存能量的数量和组成。碳水化合物过量喂养会导致碳水化合物氧化和总能量消耗的逐步增加，导致75-85%的多余能量被储存。另外，脂肪过量喂养对脂肪氧化和总能量消耗的影响最小，导致90-95%的多余能量储存。过量的膳食脂肪比过量的膳食碳水化合物导致更大的脂肪积累，并且在过度喂养期的早期差异最大。
Both the amount and composition of food eaten influence body-weight regulation. The purpose of this study was to determine whether and by what mechanism excess dietary fat leads to greater fat accumulation than does excess dietary carbohydrate. We overfed isoenergetic amounts (50% above energy requirements) of fat and carbohydrate (for 14 d each) to nine lean and seven obese men. A whole-room calorimeter was used to measure energy expenditure and nutrient oxidation on days O, 1, 7, and 14 of each overfeeding period. From energy and nutrient balances (intake-expenditure) we estimated the amount and composition of energy stored. Carbohydrate overfeeding produced progressive increases in carbohydrate oxidation and total energy expenditure resulting in 75-85% of excess energy being stored. Alternatively, fat overfeeding had minimal effects on fat oxidation and total energy expenditure, leading to storage of 90-95% of excess energy. Excess dietary fat leads to greater fat accumulation than does excess dietary carbohydrate, and the difference was greatest early in the overfeeding period.