Preparation and Characterization of Electrospun Silk Fibroin Nanofiber with Addition of 1-Ethyl-3-(3-dimethylarainopropyl) carbodiimide
Preparation and Characterization of Electrospun Silk Fibroin Nanofiber with Addition of 1-Ethyl-3-(3-dimethylarainopropyl) carbodiimide
复制标题
1-乙基-3-(3-二甲基氨基丙基)碳二亚胺静电纺丝素纳米纤维的制备及表征
DOI：
10.1134/s0965545x1105004x
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发表时间：
2011-05-01
影响因子：
1
通讯作者：
Zhang, Xueguang
中科院分区：
文献类型：
--
作者：
Zhang, Feng;Zhang, Huanxiang;Zhang, Xueguang
在静电纺丝液中加入交联剂1-乙基-3-（3-二甲氨基丙基）-碳二亚胺（EDC），直接制备了具有良好耐水性和力学性能的丝素预聚物。分析了EDC对SF浸渍毡的形态、结构和物理性能的影响。随着EDC的加入，平均纤维直径从262 nm增加到635 nm。FTIR、TG-DTA和X-射线衍射结果表明，EDC诱导了无规卷曲向β-折叠构象的转变。此外，交联剂EDC的加入明显提高了SF树脂的溶解性和力学性能。
The silk fibroin (SF) nanofiber mats with good water resistance and mechanical property were directly prepared by adding crosslinker 1-Ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC) into the electrospin solution. The effect of EDC on the morphology, structure and physical properties of SF nanofiber mats was analyzed. With the addition of EDC, the average fiber diameter increased from 262 to 635 nm. The results from FTIR, TG-DTA and X-ray diffraction showed that EDC induced the structural transition from random coil to β-sheet conformation. Furthermore, the solubility and mechanical properties of SF nanofiber mats were obviously improved when the crosslinker EDC was used.