Cytoskeletal sheets appear as universal components of mammalian eggs.
Cytoskeletal sheets appear as universal components of mammalian eggs.
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DOI：
10.1002/jez.1402630209
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发表时间：
1992-08
期刊：
影响因子：
--
通讯作者：
G. I. Gallicano;R. McGaughey;D. Capco
中科院分区：
文献类型：
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作者：
G. I. Gallicano;R. McGaughey;D. Capco
两种哺乳动物的卵已被证明含有新颖的细胞骨架元素，称为细胞骨架片，它们在三个关键的发育转变（受精、压缩和囊胚形成）的空间组织中经历特定阶段的变化。如果细胞骨架片在这些发育转变中发挥着不可或缺的作用，那么这些片也应该存在于其他哺乳动物的卵中。我们检查了另外四种物种的卵，以确定是否存在床单。我们的结果表明存在片材，并且可以根据其表面外观将它们分为两类。仓鼠和大鼠的蛋中的细胞骨架片具有光滑的表面外观，而人类、牛、猪和小鼠的蛋具有纤维状的表面外观。此外，我们观察到卵中薄片的宽度和密度（即每微米 2 的数量）存在物种特异性差异。这些物种特异性的变化可能与早期发育过程中薄片的作用有关。
The eggs of two mammalian species have been shown to contain novel cytoskeletal elements, referred to as cytoskeletal sheets, which undergo stage-specific changes in spatial organization at three key developmental transitions, fertilization, compaction, and blastocyst formation. If cytoskeletal sheets have an integral role in these developmental transitions, the sheets should be present in the eggs of other mammals as well. We examined the eggs of four additional species to determine if sheets were present. Our results indicate that sheets were present and they can be categorized into two classes based on their surface appearance. Cytoskeletal sheets in eggs of hamsters and rats have a smooth surface appearance, while eggs from humans, cows, pigs, and mice have a fibrous surface appearance. In addition, we observed that species-specific variations exist in the width of the sheets and in the density of the sheets (i.e., number per micron 2) in the eggs. These species-specific variations may relate to the role of the sheets during early development.