Diurnal salivary alpha-amylase dynamics among dementia family caregivers.
Diurnal salivary alpha-amylase dynamics among dementia family caregivers.
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痴呆症家庭护理人员的每日唾液α-淀粉酶动态。
DOI：
10.1037/hea0000430
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Zarit,StevenH
中科院分区：
文献类型：
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作者：
Liu,Yin;Granger,DouglasA;Kim,Kyungmin;Klein,LauraC;Almeida,DavidM;Zarit,StevenH
研究检查唾液α-淀粉酶（sAA）的昼夜调节与日常压力，成人日间服务（ADS）的使用，和其他adverving characteristics.MethodA样本的165个家庭照顾者的个人痴呆症（IWD）完成了为期8天的日记研究。护理人员在8天内提供了5份唾液样本。在某些日子里，护理人员提供了全部或大部分护理。在其他日子里，他们的亲戚参加了一天的一部分广告。用3水平非条件线性样条模型拟合了典型的sAA日节律。预测，然后加入到无条件模型来测试的假设，ADS的使用和日常stresss.ResultsDaily ADS的使用没有影响到昼夜SAA的调节。然而，控制日常ADS使用，在8天内更大的ADS使用与醒来后30分钟和午餐前之间更显著的上升相关，午餐前和下午晚些时候之间更显著的下降。更少的ADS天与更平坦的sAA昼夜节律。此外，更大的日常护理相关的压力源暴露与下午晚些时候较低的sAA水平有内在联系。护理相关的压力源暴露有显着的人与sAA昼夜斜率内和人与人之间的关联。此外，每天积极的经验有一个显着的人与SAA昼夜slopes.ConclusionsCaring为残疾的家庭成员可能会增加潜在的生理条件的脆弱性。从ADS使用的护理压力源缓解可能对sAA法规有一些生物行为益处。
ObjectiveThe study examined diurnal regulation of salivary alpha-amylase (sAA) in association with daily stressors, adult day services (ADS) use, and other caregiving characteristics.MethodA sample of 165 family caregivers of individuals with dementia (IWD) completed an 8-day diary study. Caregivers provided 5 saliva samples across the 8 days. On some days, caregivers provided all or most of the care. On other days, their relative attended ADS for part of the day. A 3-level unconditional linear spline model was fit to describe the typical sAA diurnal rhythms. Predictors were then added to the unconditional model to test the hypotheses on ADS use and daily stressors.ResultsDaily ADS use did not have an effect on diurnal sAA regulation. However, controlling for daily ADS use, greater ADS use over the 8 days was associated with a more prominent rise between 30 min after wake-up and before lunch, and a more prominent decline between before lunch and late afternoon. Fewer ADS days were associated with a more flattened sAA diurnal rhythm. Additionally, greater daily care-related stressor exposures had a within-person association with lower sAA levels in the late afternoon. Care-related stressor exposures had significant within-and between-person associations with sAA diurnal slopes. Furthermore, daily positive experiences had a significant between-person association with sAA diurnal slopes.ConclusionsCaring for a disabled family member may heighten the vulnerability to potential physiological conditions. Respite from care stressors from ADS use may have some biobehavioral benefits on sAA regulations.