[Bone mineral density in cosmonauts after flights lasting 4.5-6 months on the Mir orbital station].
[Bone mineral density in cosmonauts after flights lasting 4.5-6 months on the Mir orbital station].
复制标题
[在和平号轨道站飞行 4.5-6 个月后宇航员的骨矿物质密度]。
DOI：
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发表时间：
1992
影响因子：
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通讯作者：
A. Leblanc
中科院分区：
文献类型：
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作者：
V. Oganov;A. I. Grigor’ev;L. Voronin;A. Rakhmanov;A. Bakulin;V. Schneider;A. Leblanc
定量数字x线成像技术（QDR）是双光子吸收法（DPA）的最新改进，用于测量和平号轨道站第6-9次远征队成员在132至176天的太空任务后的骨矿物质密度（BMD）。总的矿物质损失平均为飞行前水平的0.4%，在大多数测试对象中，飞行后头骨、肋骨和手臂的骨密度增加，腰椎、骨盆和腿部的骨密度下降。飞行后最明显的局部矿物质损失发生在股骨近端（股骨颈和大转子-高达14%）。观察到的变化与飞行时间无关。这些发现正在与在120天（NASA）和370天（IBMP）的运动功能减退实验中进行的类似研究的结果进行比较。不同情况下肌肉骨骼负荷不足可能存在改变骨骼矿物质状态的一般机制。
A technique of quantitative digital roentgenography (QDR) being a current modification of dual photon absorptiometry (DPA) was used to measure bone mineral density (BMD) in the crewmembers of the 6-9th expeditions onboard Mir orbital station after space missions of 132 to 176 days in duration. Total mineral losses were, on average, 0.4% of a preflight level, and in the most test subjects the postflight BMD of the skull, ribs and arms increased and that of lumbar vertebrae, pelvis and legs decreased. The most marked local postflight mineral losses occurred in the proximal femur bone (the femoral neck and the greater trochanter--up to 14%). The observed changes did not depend on flight duration. These findings are being compared to the results of similar studies conducted during the 120-day (NASA) and 370-day (IBMP) hypokinesia experiments. The possibility of existing the general mechanism of modifying mineral status of the skeleton due to different situation related deficiency of musculoskeletal load.