In vitro confocal micro-PIV measurements of blood flow in a square microchannel: The effect of the haematocrit on instantaneous velocity profiles

In vitro confocal micro-PIV measurements of blood flow in a square microchannel: The effect of the haematocrit on instantaneous velocity profiles
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DOI:
10.1016/j.jbiomech.2007.01.012
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发表时间:
2007-01-01
影响因子:
2.4
通讯作者:
Yamaguchi, Takami
Yamaguchi, Takami
中科院分区:
工程技术3区
文献类型:
--
作者:
Lima, Rui;Wada, Shigeo;Yamaguchi, Takami

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一个共焦微粒图像测速(micro-PIV)系统被用来获得详细的信息,在100 μ m的平方米的微通道中的纯水(PW)和体外血液(红细胞压积高达17%)的流动的速度分布。所有的测量都是在恒定流速和低雷诺数(Re = 0.025)下在微通道的中间平面中进行的。平均合奏速度分布被发现是显着的抛物线为所有的工作流体研究。当比较三种流体的瞬时速度曲线时,我们的结果表明,曲线形状取决于红细胞压积。我们的共焦显微PIV测量结果表明,均方根(RMS)值与红细胞压积增加,这意味着它是重要的是要考虑的瞬时速度场提供的信息,即使在低Re。本研究还探讨了红细胞的瞬时速度测量的准确性的潜在影响。(c)2007爱思唯尔有限公司版权所有。
A confocal microparticle image velocimetry (micro-PIV) system was used to obtain detailed information on the velocity profiles for the flow of pure water (PW) and in vitro blood (haematocrit up to 17%) in a 100-mu m-square microchannel. All the measurements were made in the middle plane of the microchannel at a constant flow rate and low Reynolds number (Re = 0.025). The averaged ensemble velocity profiles were found to be markedly parabolic for all the working fluids studied. When comparing the instantaneous velocity profiles of the three fluids, our results indicated that the profile shape depended on the haematocrit. Our confocal micro-PIV measurements demonstrate that the root mean square (RMS) values increase with the haematocrit implying that it is important to consider the information provided by the instantaneous velocity fields, even at low Re. The present study also examines the potential effect of the RBCs on the accuracy of the instantaneous velocity measurements. (c) 2007 Elsevier Ltd. All rights reserved.