Limited Evidence for Sensory Prediction Error Responses in Visual Cortex of Macaques and Humans.
Limited Evidence for Sensory Prediction Error Responses in Visual Cortex of Macaques and Humans.
复制标题
猕猴和人类视觉皮层感官预测错误反应的证据有限。
DOI：
10.1093/cercor/bhab014
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Kohn,Adam
中科院分区：
文献类型：
--
作者：
Solomon,SelinaS;Tang,Huizhen;Sussman,Elyse;Kohn,Adam
最近提出的预测编码理论提出，每个皮质区域的神经元子集对感觉预测误差进行编码，即从高级皮质传递的预测与感觉输入之间的差异。在这里，我们测试了猕猴初级视觉皮层和 V4 区记录的尖峰反应和局部场电位 (LFP) 以及人类参与者的补充脑电图 (EEG) 头皮记录中预测错误反应的证据。我们在大多数试验中呈现了固定的视觉刺激序列，并且在一小部分试验中违反了预期的顺序。根据预测编码理论，违反模式的刺激应该会引发稳健的预测误差，但我们发现，对预期刺激和违反模式的刺激的尖峰、LFP 和 EEG 反应几乎相同。我们的结果挑战了这样的断言，即感觉皮层的基本计算主题是发出预测错误信号，至少是基于视觉刺激时间模式的预测。
A recent formulation of predictive coding theory proposes that a subset of neurons in each cortical area encodes sensory prediction errors, the difference between predictions relayed from higher cortex and the sensory input. Here, we test for evidence of prediction error responses in spiking responses and local field potentials (LFP) recorded in primary visual cortex and area V4 of macaque monkeys, and in complementary electroencephalographic (EEG) scalp recordings in human participants. We presented a fixed sequence of visual stimuli on most trials, and violated the expected ordering on a small subset of trials. Under predictive coding theory, pattern-violating stimuli should trigger robust prediction errors, but we found that spiking, LFP and EEG responses to expected and pattern-violating stimuli were nearly identical. Our results challenge the assertion that a fundamental computational motif in sensory cortex is to signal prediction errors, at least those based on predictions derived from temporal patterns of visual stimulation.