Dedicated breast computed tomography: Basic aspects
Dedicated breast computed tomography: Basic aspects
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DOI：
10.1118/1.4919441
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发表时间：
2015-06-01
期刊：
影响因子：
3.8
通讯作者：
Russo, Paolo
中科院分区：
文献类型：
--
作者：
Sarno, Antonio;Mettivier, Giovanni;Russo, Paolo
乳腺X线摄影被公认为早期发现乳腺癌的“黄金标准”，但其性能并不理想：筛查性乳腺摄影的一个限制是组织重叠，特别是对于致密乳腺。自2001年以来，美国和欧盟的几个研究小组已经开发出具有数字探测器技术的计算机断层扫描（CT）系统，专用于未压缩乳房的X射线成像（乳腺CT或BCT），用于乳腺癌筛查和诊断。这种CT技术可以追溯到20世纪70年代的初步研究，它可以克服乳房X线摄影的一些局限性，使对辐射敏感的乳腺腺体组织的辐射剂量水平与相同乳房大小和组成的双视图乳房X线摄影相似。本文介绍了在发明，开发和改进的BCT与专用扫描仪与国家的最先进的技术，包括走向商业化的初步步骤，经过十多年的研究工作进行了评估。在实验室和/或临床上进行研发。这里的重点是BCT的技术/工程方面，并概述了相关文献中报道的优点和局限性。展望了未来的研究在这一领域进行了讨论。(C)2015年美国医学物理学家协会。
X-ray mammography of the compressed breast is well recognized as the "gold standard" for early detection of breast cancer, but its performance is not ideal: One limitation of screening mammography is tissue superposition, particularly for dense breasts. Since 2001, several research groups in the USA and in the European Union have developed computed tomography (CT) systems with digital detector technology dedicated to x-ray imaging of the uncompressed breast (breast CT or BCT) for breast cancer screening and diagnosis. This CT technology-tracing back to initial studies in the 1970s-allows some of the limitations of mammography to be overcome, keeping the levels of radiation dose to the radiosensitive breast glandular tissue similar to that of two-view mammography for the same breast size and composition. This paper presents an evaluation of the research efforts carried out in the invention, development, and improvement of BCT with dedicated scanners with state-of-the-art technology, including initial steps toward commercialization, after more than a decade. of R&D in the laboratory and/or in the clinic. The intended focus here is on the technological/engineering aspects of BCT and on outlining advantages and limitations as reported in the related literature. Prospects for future research in this field are discussed. (C) 2015 American Association of Physicists in Medicine.