Rearrangement of beta-chloro N-oxides to hydroxylamines: opening of the oxazetidinium intermediate by different nucleophiles.
Rearrangement of beta-chloro N-oxides to hydroxylamines: opening of the oxazetidinium intermediate by different nucleophiles.
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β-氯氮氧化物重排为羟胺：不同亲核试剂打开恶氮杂丁鎓中间体。
DOI：
10.1021/jo900031e
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Wefelscheid UK
中科院分区：
文献类型：
--
作者：
Wefelscheid UK
β-氯氧化物对羟胺的重排具有立体特异性，这与环恶氮杂啶中间体的存在一致。后者以一系列亲核试剂（羧酸盐、氰化物、叠氮化物和硫醇）开启。
The rearrangement of β-chloroN-oxides to hydroxylamines is stereospecific in accord with the presence of a cyclic oxazetidinium intermediate. The latter opens with a range of nucleophiles (carboxylates, cyanide, azide, and thiols).