Waist circumference, blood pressure, and lipid components of the metabolic syndrome
Waist circumference, blood pressure, and lipid components of the metabolic syndrome
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DOI：
10.1016/j.jpeds.2006.08.075
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发表时间：
2006-12-01
影响因子：
5.1
通讯作者：
Arslanian, Silva A.
中科院分区：
文献类型：
--
作者：
Lee, Sojung;Bacha, Fida;Arslanian, Silva A.
目的探讨腰围（WC）能否独立于体重指数（BMI）百分位数预测青少年代谢综合征的血压（BP）和脂质成分。研究设计研究小组由70名非裔美国青年和97名白人青年组成。结果测量包括血压、血脂和腹部脂肪组织（AT）。结果BMI百分位数和WC与昼夜收缩压、舒张压、甘油三酯（TG）、高密度脂蛋白（HDL）、TG/HDL比值均有显著相关性（P < 0.05），与种族无关。在非裔美国人和白种人中，WC与白天保持显著相关（P < 0.05） （r = 0.50）。59)和夜间(r = .49和。在白种人中，TG， HDL， TG/HDL和极低密度脂蛋白在控制BMI百分位数后。在考虑了年龄、环境和种族因素后，BMI百分位数增加WC使收缩压方差（R-2）增加15% （P < 0.05）。BMI百分位数中WC的加入分别解释了TG和HDI的3%和7%的方差（P < 0.05）。结论在BMI百分位数的基础上加入WC可显著提高儿童肥胖相关健康风险的预测能力。这一观察结果支持了这样一种观点，即体重应与BDI百分位数一起纳入儿童肥胖评估，以确定那些因腹部脂肪过多而面临更高健康风险的儿童。
Objectives To examine whether waist circumference (WC) predicts blood pressure (BP) and lipid components of the metabolic syndrome independent of body mass index (BMI) percentile in youths.Study design The study group comprised 70 African-American youths and 97 Caucasian youths. Outcome measures included BP, lipid profile, and abdominal adipose tissue (AT).Results Both BMI percentile and WC were significantly (P < .05) associated with daytime and nighttime systolic and diastolic BP, triglycerides (TG), high-density lipoprotein (HDL), and TG/HDL ratio independent of race. In African-Americans and Caucasians, WC remained a significant (P < .05) correlate of daytime (r = .50 and .59, respectively) and nighttime (r = .49 and .62, respectively) systolic BP, and in Caucasians, TG, HDL, TG/HDL and very-low-density lipoprotein after controlling for BMI percentile. After accounting for age, set, and race, the addition of WC to BMI percentile increased the variance (R-2) in systolic BP by 15% (P < .05). The inclusion of WC with BMI percentile explained an additional 3% and 7% of the variance in TG and HDI, respectively (P < .05).Conclusions The prediction of childhood obesity-related health risks is significantly improved by the inclusion of WC in addition to BMI percentile. This observation supports the notion that WC should be included in the evaluation of childhood obesity along with BDI percentile to identify those at increased health risks due to excess abdominal fat.