Virilizing tumors of the ovary: imaging features

Virilizing tumors of the ovary: imaging features
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DOI:
10.1046/j.1469-0705.2000.00123.x
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发表时间:
2000-05-01
影响因子:
7.1
通讯作者:
Wagner, BJ
Wagner, BJ
中科院分区:
医学1区
文献类型:
--
作者:
Outwater, EK;Marchetto, B;Wagner, BJ

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目的卵巢男性化肿瘤是一种罕见的临床问题的原因。这些肿瘤的影像学特征的报告是基于病例报告。本研究的目的是根据更大的转诊人群确定这些转变者的成像特征谱。患者和方法检索武装部队病理学研究所的病例记录,寻找男性化的临床证据,表现为切除的性索间质和类固醇细胞卵巢肿瘤。14例男性化肿瘤患者的记录和影像学研究。所有可用的影像学研究(骨盆超声检查(11例),骨盆CT扫描(5名患者),骨盆MRI检查(2例患者),以及骨盆平片(4名患者)由3名放射科医生独立审查腹水、钙化、固体部分百分比,结果CT和/或B超表现为实性或多实性者占69%。实性组织的数量因肿瘤类型而异,颗粒细胞瘤以囊性为主。肿块呈等回声(82%)或低回声(18%)。腹水是一种罕见的发现(23%)。这些肿瘤中只有少数(14%)在成像研究中钙化。6个翻转器的平均尺寸为5.0 cm或更小,2个小于3.0 cm。所有病例均为I期肿瘤。结论卵巢男性化肿瘤多为典型的实性、非钙化性肿瘤,临床表现局限于卵巢,与腹水无关。外观的变化部分取决于肿瘤类型。许多是小的,可能很难识别为一个肿块形态。
Aim Virilizing tumors of the ovary are an uncommon cause of a common clinical problem. The reported imaging features of these tumors are based on case reports. The purpose of this study was to determine the spectrum of imaging characteristics of these turners based on a larger referral population.Patients and Methods Case records from the Armed Forces Institute of Pathology were searched for clinical evidence of virilization as a presentation of an excised sex cord-stromal and steroid cell ovarian tumor. Records and imaging studies on 14 patients with virilizing tumors were found. All available imaging studies (ultrasound studies of the pelvis (11 patients), CT scans of the pelvis (five patients), MRI examinations of the pelvis (two patients), and plain films of the pelvis (four patients) were reviewed by three radiologists independently for ascites, calcification, percent solid portion, echogenicity and attenuation.Results On CT and/or ultrasound most (69%) of the tumors appeared to be solid or mostly solid. The amount of solid tissue varied with the tumor type, granulosa cell tumors were predominantly cystic. The masses were isoechoic (82%) or hypoechoic (18%). Ascites was an infrequent (23%) finding. Only a minority of these tumors (14%) were calcified on imaging studies. Six turners were 5.0 cm or less in mean size, and two less than 3.0 cm in size. All cases were stage I tumors at presentation.Conclusion The majority of virilizing turners of the ovary are typically solid, noncalcified, confined to the ovary at presentation, and not associated with ascites. Variability in appearance depends in part on tumor type. Many are small and may be difficult to recognize as a mass morphologically.