Prevalence of depression and its association with quality of life in clinically stable patients with COVID-19
Prevalence of depression and its association with quality of life in clinically stable patients with COVID-19
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DOI：
10.1016/j.jad.2020.06.033
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发表时间：
2020-10-01
影响因子：
6.6
通讯作者：
Xiang, Yu-Tao
中科院分区：
文献类型：
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作者：
Ma, Yu-Fen;Li, Wen;Xiang, Yu-Tao
引言：精神健康问题的高风险与2019年冠状病毒病（COVID-19）有关。本研究旨在探讨临床稳定的COVID-19患者抑郁症状（以下简称抑郁）的患病率及其与生活质量（QOL）的关系。方法：对湖北省5家COVID-19定点隔离医院的COVID-19患者进行在线调查。结果：共纳入770名被试。抑郁症患病率为43.1%（95%CI：39.6%~ 46.6%）。二元逻辑回归分析发现，家庭成员感染COVID-19（OR = 1.51，P = 0.01），患有重度COVID-19感染（OR = 1.67，P = 0.03），男性（OR=0.53，P < 0.01）、频繁使用社交媒体获取COVID-19相关信息（OR = 0.65，P < 0.01）与抑郁独立相关。结论：抑郁症在临床稳定的COVID-19患者中高度流行。定期筛查和适当的治疗抑郁症是迫切需要为这一人群。
Introduction: High risk of mental health problems is associated with Coronavirus Disease 2019 (COVID-19). This study explored the prevalence of depressive symptoms (depression hereafter) and its relationship with quality of life (QOL) in clinically stable patients with COVID-19.Methods: This was an online survey conducted in COVID-19 patients across five designated isolation hospitals for COVID-19 in Hubei province, China. Depression and QOL were assessed with standardized instruments.Results: A total of 770 participants were included. The prevalence of depression was 43.1% (95%CI: 39.6%-46.6%). Binary logistic regression analysis found that having a family member infected with COVID-19 (OR = 1.51, P = 0.01), suffering from severe COVID-19 infection (OR = 1.67, P = 0.03), male gender (OR=0.53, P < 0.01), and frequent social media use to obtain COVID-19 related information (OR = 0.65, P < 0.01) were independently associated with depression. Patients with depression had lower QOL than those without.Conclusion: Depression is highly prevalent in clinically stable patients with COVID-19. Regular screening and appropriate treatment of depression are urgently warranted for this population.