Improvement of antioxidant potential in rats consuming feathers protein hydrolysate obtained by fermentation of the keratinolytic bacterium, Bacillus pumilus A1

Improvement of antioxidant potential in rats consuming feathers protein hydrolysate obtained by fermentation of the keratinolytic bacterium, Bacillus pumilus A1
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食用由角蛋白分解细菌短小芽孢杆菌 A1 发酵获得的羽毛蛋白水解物,可提高大鼠的抗氧化能力

DOI:
10.5897/ajb11.1741
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发表时间:
2012
期刊:
影响因子:
--
通讯作者:
M. Nasri
M. Nasri
中科院分区:
--
文献类型:
--
作者:
Nahed Fakhfakh;M. Gargouri;Ines Dahmen;Alya Sellami;Abdelfattah El;Feki;M. Nasri

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研究了短小芽孢杆菌A1菌株发酵产生的羽毛蛋白水解物(FPH)的体外和体内抗氧化活性。用DNA刻痕和亚铁肼方法对FPH的抗氧化活性进行了评价,结果表明,FPH具有重要的抗氧化潜力。有趣的是,在饲料中添加该水解物(2.5%和5%)后,大鼠肝、肾、心脏、脑和小脑中硫代巴比妥酸试剂物质(TBARS)的比率和酶类抗氧化剂(超氧化物歧化酶、谷胱甘肽过氧化物酶和过氧化氢酶)活性显著降低。然而,在标准食物中添加2.5%的未经处理的羽毛粉或5%的大豆与TBARS率和酶的抗氧化活性的增加有关。这些结果表明,FPH可以作为补充蛋白质和天然抗氧化剂在动物饲料配方中使用。
The in vitro and in vivo antioxidant activities of feathers protein hydrolysate (FPH), produced by fermentation with the keratinolytic bacterium, Bacillus pumilus strain A1, were evaluated. The antioxidant activities of FPH, evaluated using DNA nicking and ferrozine assays, demonstrate that FPH present an important antioxidant potential. Interestingly, the addition of this hydrolysate (2.5 and 5%) to the feed of rats caused a significant decrease in the rate of thiobarbutiric acid reagent substances (TBARS) and the enzymatic antioxidants activities (superoxide dismutase, glutathione peroxidase and catalase) in liver, kidney, heart, brain and cerebella, as compared to the control. However, the supplementation of the standard food by 2.5% of untreated feather meal or 5% of soya is associated with an increase of the TBARS rate and enzymatic antioxidant activities. These results indicate that FPH may be useful as supplementary proteins and natural antioxidant in animal feed formulation.
“1972政权”日本安保体系下的台湾(中文)
DOI: --
发表时间: 2022
期刊:
影响因子: --
作者:
Barrett;B;Ohta;H.;and Trencher;G. "Prospects for Acceleration of Socio-Technical Transitions for Deep Decarbonization," pp. 400-414;青山瑠妙;福田円;舒旻「中国:EUとの脆弱な相互依存」pp. 247-271;福田円;青山瑠妙;青山瑠妙;青山瑠妙;福田円;青山瑠妙;福田円
通讯作者: 福田円