T2-weighted cardiovascular magnetic resonance in acute cardiac disease.
T2-weighted cardiovascular magnetic resonance in acute cardiac disease.
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DOI：
10.1186/1532-429x-13-13
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发表时间：
2011-02-18
期刊：
影响因子：
--
通讯作者：
Friedrich MG
中科院分区：
文献类型：
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作者：
Eitel I;Friedrich MG
心血管磁共振（CMR）使用t2加权序列可以显示心肌水肿。与以前的方案相比，较新的脉冲序列具有显著改善的图像质量，增加了其临床效用。心肌水肿的评估在各种与急性心肌损伤相关的临床环境中提供有用的增量诊断和预后信息。在急性胸痛患者中，t2加权CMR能够识别急性或近期心肌缺血损伤，并已被用于区分急性冠脉综合征（ACS）与非ACS以及急性与慢性心肌梗死。t2加权CMR也可用于确定再灌注和非再灌注梗死的危险区域。当结合对比增强成像时，可以量化挽救面积，从而量化早期冠状动脉血运重建的成功。心肌挽救的预后价值的有力证据使其成为临床试验的主要终点。本文综述了t2加权CMR在急性心脏病中的临床应用，并对未来的发展进行了展望。米利都的泰勒斯（公元前624年-公元前546年）
Cardiovascular magnetic resonance (CMR) using T2-weighted sequences can visualize myocardial edema. When compared to previous protocols, newer pulse sequences with substantially improved image quality have increased its clinical utility. The assessment of myocardial edema provides useful incremental diagnostic and prognostic information in a variety of clinical settings associated with acute myocardial injury. In patients with acute chest pain, T2-weighted CMR is able to identify acute or recent myocardial ischemic injury and has been employed to distinguish acute coronary syndrome (ACS) from non-ACS as well as acute from chronic myocardial infarction. T2-weighted CMR can also be used to determine the area at risk in reperfused and non-reperfused infarction. When combined with contrast-enhanced imaging, the salvaged area and thus the success of early coronary revascularization can be quantified. Strong evidence for the prognostic value of myocardial salvage has enabled its use as a primary endpoint in clinical trials. The present article reviews the current evidence and clinical applications for T2-weighted CMR in acute cardiac disease and gives an outlook on future developments. "The principle of all things is water" Thales of Miletus (624 BC - 546 BC)