Comorbidity rates of depression and anxiety in first episode psychosis: A systematic review and meta-analysis

Comorbidity rates of depression and anxiety in first episode psychosis: A systematic review and meta-analysis
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首发精神病中抑郁和焦虑的共病率:系统评价和荟萃分析

DOI:
10.1016/j.schres.2019.11.035
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发表时间:
2019
影响因子:
4.5
通讯作者:
A. Morrison
A. Morrison
中科院分区:
医学2区
文献类型:
--
作者:
Rebecca S. Wilson;A. Yung;A. Morrison

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Anxiety and depression symptoms are frequently experienced by individuals with psychosis, although prevalence rates have not been reviewed in first-episode psychosis (FEP). The aim of this systematic review was to focus on the prevalence rates for both anxiety and depression, comparing the rates within the same study population. A systematic review and meta-analysis was completed for all studies measuring both anxiety and depression in FEP at baseline. The search identified 6040 citations, of whichn= 10 met inclusion criteria. These reported 1265 patients (age 28.3 ± 9.1, females: 39.9%) with diagnosed FEP. Studies which used diagnosis to define comorbidity count were included in separate meta-analyses for anxiety and depression, although the heterogeneity was high limiting interpretation of separate prevalence rates. A random-effects meta-analysis also compared the mean difference between anxiety and depression within the same studies. We show that anxiety and depression co-occur at a similar rate within FEP, although the exact rates are not reliable due to the heterogeneity between the small number of studies. Future research in FEP should consider routinely measuring anxiety and depression using continuous self-report measures of symptoms. Clinically we recommend that both anxiety and depression are equally targeted during psychological intervention in FEP, together with the psychotic symptoms.
精神分裂症继发性抑郁症的诊断:对 DSM-IV 的影响。
DOI: 10.1093/schbul/17.1.75
发表时间: 1991
影响因子: 6.6
作者:
Siris,SG
通讯作者: Siris,SG
DOI: 10.1093/oxfordjournals.schbul.a007046
发表时间: 2003-01-01
影响因子: 6.6
作者:
McGorry, PD;Yung, AR;Phillips, LJ
通讯作者: Phillips, LJ
首发精神分裂症的抑郁症。
DOI: 10.1176/ajp.150.11.1643
发表时间: 1993
期刊: The American journal of psychiatry
影响因子: --
作者:
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通讯作者: Lieberman,J