Evolution of the wall shear stresses during the progressive enlargement of symmetric abdominal aortic aneurysms
Evolution of the wall shear stresses during the progressive enlargement of symmetric abdominal aortic aneurysms
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DOI：
10.1017/s002211200600036x
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发表时间：
2006-08-10
影响因子：
3.7
通讯作者：
Lasheras, J. C.
中科院分区：
文献类型：
--
作者：
Salsac, A. -V.;Sparks, S. R.;Lasheras, J. C.
腹主动脉瘤(AAA)扩大不同阶段壁面切应力(WSS)和壁面切应力梯度(GWSS)的时空分布变化对于了解AAA血管病变的病因和进展具有重要意义，因为它们主要通过对内皮细胞形态、功能和代谢的影响而影响管壁结构的完整性。用粒子图像测速仪(PIV)对体外动脉瘤模型进行测量，同时系统地改变其几何参数。已经表明，即使在疾病的非常早期阶段，即直径增大
The changes in the evolution of the spatial and temporal distribution of the wall shear stresses (WSS) and gradients of wall shear stresses (GWSS) at different stages of the enlargement of an abdominal aortic aneurysm (AAA) are important in understanding the aetiology and progression of this vascular disease since they affect the wall structural integrity, primarily via the changes induced on the shape, functions and metabolism of the endothelial cells. Particle image velocimetry (PIV) measurements were performed in in vitro aneurysm models, while changing their geometric parameters systematically. It has been shown that, even at the very early stages of the disease, i.e. increase in the diameter