ANTIBACTERIAL AND ANTIVIRAL ACTIVITY OF CAMEL MILK PROTECTIVE PROTEINS
ANTIBACTERIAL AND ANTIVIRAL ACTIVITY OF CAMEL MILK PROTECTIVE PROTEINS
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DOI：
10.1017/s0022029900030417
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发表时间：
1992-05-01
影响因子：
2.1
通讯作者：
ASSAF, R
中科院分区：
文献类型：
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作者：
ELAGAMY, ESI;RUPPANNER, R;ASSAF, R
溶菌酶（LZ）、乳铁蛋白（LF）。乳过氧化物酶（LP）。从骆驼乳中提取免疫球蛋白G和分泌型免疫球蛋白A。这些保护性蛋白质的活性进行了测定，对Lartococcus lactis subsp.奶油大肠埃希菌金黄色葡萄球菌。鼠伤寒沙门氏菌和轮状病毒。比较白色LZ的活性。牛LZ和牛LF也被提出。骆驼乳LZ的抑菌谱与鸡蛋白色LZ相似。与牛乳LZ不同。牛乳和骆驼乳LF的抗菌活性谱相似。骆驼乳LP对革兰氏阳性菌株具有抑菌作用，对革兰氏阴性培养物具有杀菌作用。免疫球蛋白对细菌的作用很小，但骆驼奶中发现了高滴度的抗轮状病毒抗体。LP系统对
Lysozyme (LZ), lactoferrin (LF). lactoperoxidase (LP). immunoglobulin G and secretory immunoglobulin A were extracted from camel milk. The activity of these protective proteins was assayed against Lartococcus lactis subsp. cremoris. Escherichia coli. Staphylococcus aureus. Salmonella typhimurium and rotavirus. Comparative activities of egg white LZ. bovine LZ and bovine LF are also presented. The antibacterial activity spectrum of camel milk LZ was similar to that of egg white LZ. and differed from bovine milk LZ. Bovine and camel milk LF antibacterial activity spectra were similar. The camel milk LP was bacteriostatic against the Gram-positive strains and was bactericidal against Gram-negative cultures. The immunoglobulins had little effect against the bacteria but high titres of antibodies against rotavirus were found in camel milk. The LP system was ineffective against