Central nervous system processing of emotions in children with nocturnal enuresis and attention-deficit/hyperactivity disorder
Central nervous system processing of emotions in children with nocturnal enuresis and attention-deficit/hyperactivity disorder
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DOI：
10.1111/apa.12676
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发表时间：
2014-08-01
期刊：
影响因子：
3.8
通讯作者：
von Gontard, Alexander
中科院分区：
文献类型：
--
作者：
Equit, Monika;Becker, Anna;von Gontard, Alexander
目的：夜间遗尿症（NE）和注意缺陷多动障碍（ADHD）是儿童期常见的疾病。方法：对13例NE、13例ADHD、14例NE + ADHD和14例正常儿童的情绪中枢加工进行了研究。使用标准化方法记录声诱发电位。对于事件相关电位，呈现阳性、阴性和中性图片，并评价250-450、450-650和650-850 msec的时间间隔。假设进行了测试与重复测量的方差analysis.Results：在额叶区，NE儿童表现出更强烈的反应，积极和消极的图片比控制测量与事件相关电位。观看积极的图片，NE + ADHD儿童与ADHD儿童在中央和顶叶以及顶叶区域的所有类型的刺激不同。NE + ADHD儿童的反应最强。ADHD儿童与对照组没有差异。有一个非特异性的相互作用效应的声诱发电位在NE儿童相比controls.Conclusion：NE儿童处理情绪与ADHD儿童和对照组不同。NE + ADHD的儿童处理情绪最强烈，显示中枢神经系统的相互作用，不能单独用每种疾病来解释。
Aim: Nocturnal enuresis (NE) and attention-deficit/hyperactivity disorder (ADHD) are common in childhood. We analysed the central processing of emotions in children with NE, ADHD, NE + ADHD and controls.Methods: We examined 13 children with NE, 13 with ADHD, 14 with NE + ADHD and 14 controls. Acoustic evoked potentials were recorded using standardised methodology. For the event-related potentials, positive, negative and neutral pictures were presented and time intervals of 250-450, 450-650 and 650-850 msec evaluated. Hypotheses were tested with repeated-measures analyses of variance.Results: In the frontal region, children with NE showed more intense responses to positive and negative pictures than controls measured with event-related potentials. Viewing positive pictures, children with NE + ADHD differed from children with ADHD in the central and parietal and for all types of stimuli in the parietal region. Children with NE + ADHD elicited the strongest responses. Children with ADHD did not differ from controls. There was an unspecific interaction effect of the acoustic evoked potentials in children with NE compared to the controls.Conclusion: Children with NE processed emotions differently from children with ADHD and controls. Children with NE + ADHD processed emotions the most intense, displaying interaction effects of the central nervous system that cannot be explained by each disorder alone.