Anxiety and poor glycemic control: A meta-analytic review of the literature
Anxiety and poor glycemic control: A meta-analytic review of the literature
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DOI：
10.2190/klgd-4h8d-4ryl-twq8
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发表时间：
2002-01-01
影响因子：
2
通讯作者：
Lustman, PJ
中科院分区：
文献类型：
--
作者：
Anderson, RJ;Grigsby, AB;Lustman, PJ
目的：确定成人 I 型或 2 型糖尿病患者的焦虑是否与血糖控制不良有关。方法：使用 MEDLINE、PubMed 和 PsycINFO 数据库来查找测量焦虑与血糖控制之间关系的研究。荟萃分析程序用于将研究结果转换为通用指标，计算效应大小 (ES)，并对集体数据进行统计分析。结果：检索程序确定了 12 项研究，其中 11 项（92%）满足纳入荟萃分析的标准。在整个组中，焦虑与血糖控制无关（p = 0.19），尽管 ES 具有轻微的统计显着性（ES = 0.09，95% Cl = 0.04 至 0.14）。在通过诊断访谈确定焦虑的研究中，焦虑与高血糖相关（p = 0.003），ES 也具有统计学显着性（ES：0.25，95% CI = 0.10 至 0.38）。结论：现有文献表明，糖尿病患者的焦虑症与高血糖有关。需要更多的研究来确认这种关系的严重程度，阐明调节因素和因果因素，并确定成功治疗焦虑是否可以改善血糖控制。
Objective: To determine whether anxiety is associated with poor glycemic control in adults with type I or type 2 diabetes. Method: MEDLINE, PubMed, and PsycINFO databases were used to locate studies that measured the association of anxiety with glycemic control. Meta-analytic procedures were used to convert the findings to a common metric, compute effect sizes (ES), and statistically analyze the collective data. Results: The search procedures identified 12 studies, 11 (92 percent) of which satisfied the criteria for inclusion in the meta-analysis. In this overall group, anxiety was not associated with glycemic control (p = 0.19), although the ES was marginally statistically significant (ES = .09, 95 percent Cl = 0.04 to 0.14). In studies that determined anxiety from diagnostic interviews, anxiety was associated with hyperglycemia (p = 0.003) and the ES was also statistically significant (ES: 0.25, 95 percent CI = 0.10 to 0.38). Conclusions: The existing literature suggests that anxiety disorders are associated with hyperglycemia in diabetic patients. Additional studies are required to confirm the magnitude of the relationship, to elucidate moderating and causal factors, and to determine whether successful treatment of anxiety improves glycemic control.