Reactivation of ocular toxoplasmosis during pregnancy

Reactivation of ocular toxoplasmosis during pregnancy
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DOI:
10.1111/j.1471-0528.2004.00302.x
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发表时间:
2005-02-01
影响因子:
5.8
通讯作者:
Peyron, F
Peyron, F
中科院分区:
医学1区
文献类型:
--
作者:
Garweg, JG;Scherrer, J;Peyron, F

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我们希望评估免疫功能正常的女性在怀孕期间眼弓形虫病是否会重新激活,以及这种重新激活是否仅限于眼睛或胎儿是否面临垂直传播的风险。为此,我们回顾性检查了 18 名在 35 次怀孕期间患有眼部弓形体病的女性。在这 18 名患者中,有 7 名患者在 7 次怀孕期间出现复发。由于母亲功能受损的潜在风险以及疾病垂直传播给胎儿的可能性,我们建议在怀孕期间仔细跟踪此类病例,直到更充分地了解问题的严重程度。
We wished to assess whether ocular toxoplasmosis can be reactivated during pregnancy in immunocompetent females, and whether such reactivation is confined to the eye or whether the fetus is exposed to the risk of vertical transmission. For this purpose, we retrospectively examined 18 females with ocular toxoplasmosis during the course of 35 pregnancies. Of these 18 patients, seven developed recurrences during seven pregnancies. Due to the potential risk of functional damage to the mother and the possibility of vertical disease transmission to the fetus, we suggest following such cases carefully during pregnancy until the dimensions of the problem are more fully appreciated.