Fat-water separated delayed hyperenhanced myocardial infarct imaging
Fat-water separated delayed hyperenhanced myocardial infarct imaging
复制标题
DOI：
10.1002/mrm.21685
复制
发表时间：
2008-09-01
影响因子：
3.3
通讯作者：
Goldfarb, James W.
中科院分区：
文献类型：
--
作者：
Goldfarb, James W.
与心肌梗死(MI)相关的脂肪沉积已被报道为一种常见现象。磁共振成像(MRI)能够利用T-1敏感的对比增强序列有效地检测MI，并通过其共振频移来检测FAT。在这项工作中，证明了脂肪和水分离应用于传统的延迟超增强(DHE)MI成像技术的可行性。三点Dixon采集和重建与反转恢复梯度回波脉冲序列相结合。这使得注射造影剂后，脂肪和水的分离以及T敏感成像成为可能。这项技术在模体实验和三名慢性心肌梗死患者中得到了验证。梗死区在水成像中被明确定义为常规高强化。在两个病例中，脂肪沉积在脂肪图像中被检测到，并经平扫反相成像证实。
Fat deposition associated with myocardial infarction (MI) has been reported as a commonly occurring phenomenon. Magnetic resonance imaging (MRI) has the ability to efficiently detect MI using T-1-sensitive contrast-enhanced sequences and fat via its resonant frequency shift. In this work, the feasibility of fat-water separation applied to the conventional delayed hyperenhanced (DHE) MI imaging technique is demonstrated. A three-point Dixon acquisition and reconstruction was combined with an inversion recovery gradient-echo pulse sequence. This allowed fat-water separation along with T, sensitive imaging after injection of a gadolinium contrast agent. The technique is demonstrated in phantom experiments and three subjects with chronic MI. Areas of infarction were well defined as conventional hyperenhancement in water images. In two cases, fatty deposition was detected in fat images and confirmed by precontrast opposed-phase imaging.