Future directions in breeding for disease resistance in aquaculture species
Future directions in breeding for disease resistance in aquaculture species
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DOI：
10.1590/s1806-92902017000600010
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发表时间：
2017-06-01
期刊：
影响因子：
--
通讯作者：
Houston, Ross D.
中科院分区：
文献类型：
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作者：
Houston, Ross D.
传染病是所有水产养殖品种的主要制约因素。大多数养殖鱼类和贝类的生产是基于有限或没有选择性育种的种群。由于抗病几乎是普遍可遗传的，因此有巨大的潜力来选择提高对关键疾病的抗性。这篇简短的综述讨论了目前培育更具抗性的水产养殖种群的方法，重点介绍了成功案例和当前的瓶颈。本文讨论了目前基因组选择在抗病育种中的实施情况，以及在水产养殖中更大规模实施和改进的途径。强调了未来的方向，包括基因组编辑工具的潜力，用于绘制抗病性状的致病变异，以及培育具有增强抗病能力的水产养殖动物。
Infectious disease is a major constraint for all species produced via aquaculture. The majority of farmed fish and shellfish production is based on stocks with limited or no selective breeding. Since disease resistance is almost universally heritable, there is huge potential to select for improved resistance to key diseases. This short review discusses the current methods of breeding more resistant aquaculture stocks, with success stories and current bottlenecks highlighted. The current implementation of genomic selection in breeding for disease resistance and routes to wider-scale implementation and improvement in aquaculture are discussed. Future directions are highlighted, including the potential of genome editing tools for mapping causative variation underlying disease resistance traits and for breeding aquaculture animals with enhanced resistance to disease.