Prospective randomized trial of high versus low negative pressure suction in management of chyle fistula after neck dissection for metastatic thyroid carcinoma
Prospective randomized trial of high versus low negative pressure suction in management of chyle fistula after neck dissection for metastatic thyroid carcinoma
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DOI：
10.1002/hed.21979
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发表时间：
2012-12-01
影响因子：
2.9
通讯作者：
Koch, Wayne M.
中科院分区：
文献类型：
--
作者：
Wu, Gaosong;Chang, Xiaofei;Koch, Wayne M.
背景负压引流术是治疗乳糜瘘的有效方法。然而，负压的最佳水平尚未确定。因此，我们进行了一项前瞻性随机试验来解决这个问题。方法将21例乳糜瘘患者随机分为高负压吸引组（-600 mmHg, n = 10）和低负压吸引组（-125 mmHg, n = 11）。比较两组患者漏液时间、住院时间及并发症发生率。结果所有患者均采用保守治疗，无手术干预。HNPS组乳糜漏的中位持续时间和住院时间明显短于LNPS组：分别为4天和7天（p = 0.0048）和5天和11天（p = 0.0107）。结论负吸引是治疗乳糜瘘的有效方法，HNPS比LNPS更有效。(c) 2011 Wiley期刊公司头颈，2011年
Background Negative pressure drainage has been shown to be an effective treatment of chyle fistula. However, the optimal level of negative pressure has not been determined. We therefore conducted a prospective randomized trial to address this issue. Methods In all, 21 patients with chyle fistula were randomly assigned to a high negative pressure suction (HNPS) group (-600 mmHg, n = 10) or low negative pressure suction (LNPS) group (-125 mmHg, n = 11). The duration of drain leakage and hospital stay, and the incidence of complications were compared between the 2 groups. Results All patients were successfully treated with conservative management without surgical intervention. The median durations of chyle leakage and hospital stay were significantly shorter in the HNPS group compared with the LNPS group: 4 versus 7 days (p = .0048) and 5 versus 11 days (p = .0107), respectively. Conclusions Negative suction was demonstrated to be highly effective in the management of chyle fistula, and HNPS appeared to be more efficient than LNPS. (c) 2011 Wiley Periodicals, Inc. Head Neck, 2011