Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025
Global, regional, and national burden and trend of diabetes in 195 countries and territories: an analysis from 1990 to 2025
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195 个国家和地区的全球、区域和国家糖尿病负担和趋势：1990 年至 2025 年分析
DOI：
10.1038/s41598-020-71908-9
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发表时间：
2020-09-08
影响因子：
4.6
通讯作者：
Shan, Peng-Fei
中科院分区：
文献类型：
--
作者：
Lin, Xiling;Xu, Yufeng;Shan, Peng-Fei
糖尿病是死亡和预期寿命缩短的主要原因。我们旨在按类型、年份、地区和社会经济状况估算过去28年195个国家和地区的糖尿病负担，为实现世界卫生组织《预防和控制非传染性疾病全球行动计划》2025年的目标提供信息。数据来自2017年全球疾病负担研究。总体而言，自1990年以来，全球糖尿病负担显着增加。 糖尿病相关疾病的负担在不同地区和国家之间差异很大。 2017年，全球与糖尿病相关的发病率、患病率、死亡和伤残调整生命年（DALY）分别为2290万、4.760亿、137万和6790万，预计到2025年将分别达到2660万、5.709亿、159万和7930万。全球2型糖尿病负担趋势与总糖尿病（包括1型糖尿病和2型糖尿病）的趋势相似，而全球1型糖尿病年龄标准化死亡率和伤残调整生命年（DALY）下降。在全球范围内，代谢风险（高 BMI）和行为因素（不适当的饮食、吸烟和低体力活动）是糖尿病死亡和伤残调整生命年 (DALY) 的主要原因。这些估计可用于糖尿病预防和治疗的政策制定、优先事项设定和资源分配。
Diabetes mellitus is a leading cause of mortality and reduced life expectancy. We aim to estimate the burden of diabetes by type, year, regions, and socioeconomic status in 195 countries and territories over the past 28 years, which provide information to achieve the goal of World Health Organization Global Action Plan for the Prevention and Control of Noncommunicable Diseases in 2025. Data were obtained from the Global Burden of Disease Study 2017. Overall, the global burden of diabetes had increased significantly since 1990. Both the trend and magnitude of diabetes related diseases burden varied substantially across regions and countries. In 2017, global incidence, prevalence, death, and disability-adjusted life-years (DALYs) associated with diabetes were 22.9 million, 476.0 million, 1.37 million, and 67.9 million, with a projection to 26.6 million, 570.9 million, 1.59 million, and 79.3 million in 2025, respectively. The trend of global type 2 diabetes burden was similar to that of total diabetes (including type 1 diabetes and type 2 diabetes), while global age-standardized rate of mortality and DALYs for type 1 diabetes declined. Globally, metabolic risks (high BMI) and behavioral factors (inappropriate diet, smoking, and low physical activity) contributed the most attributable death and DALYs of diabetes. These estimations could be useful in policy-making, priority setting, and resource allocation in diabetes prevention and treatment.