Cortical and subcortical networks underlying syncopated and synchronized coordination revealed using fMRI
Cortical and subcortical networks underlying syncopated and synchronized coordination revealed using fMRI
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DOI：
10.1002/hbm.10065
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发表时间：
2002-12-01
影响因子：
4.8
通讯作者：
Kelso, JAS
中科院分区：
文献类型：
--
作者：
Mayville, JM;Jantzen, KJ;Kelso, JAS
在节拍（同步）和非节拍（切分）协调模式之间的内在难度差异是众所周知的。同步通常是相当容易的，并且一旦开始，可以在几乎没有明显注意力需求的情况下进行。切分往往是困难的，即使它被描述为一个简单的，相移版本的同步模式。我们假设，切分，不像同步，是有组织的一个周期的基础上，从而施加更大的准备和注意力的要求，中枢神经系统。为了验证这一假设，我们使用功能磁共振成像来测量切分和同步听觉刺激过程中的BOLD反应。我们发现，皮质和皮质下的分布。有意地与外部节拍器协调运动所涉及的区域取决于所采用的定时模式。同步和切分模式都需要激活对侧感觉运动和尾侧辅助运动皮层以及（主要是同侧）小脑。然而，脱离节拍不仅需要小脑的额外激活，还需要招募另一个网络，包括基底神经节、背外侧前运动区、吻侧辅助运动区、前额叶和颞叶联合皮层。在同步过程中，没有发现比更活跃的区域。切分音参与切分的皮层和皮层下区域的功能作用支持这样一个假设，即同步需要很少的准备和监测，切分动作是在每个感知-动作周期中单独计划和执行的。(C)2002 Wiley-Liss，Inc.
Inherent differences in difficulty between on the beat (synchronization) and off the beat (syncopation) coordination modes are well known. Synchronization is typically quite easy and, once begun, may be carried out with little apparent attention demand. Syncopation tends to be difficult, even though it has been described as a simple, phase-shifted version of a synchronized pattern. We hypothesize that syncopation, unlike synchronization, is organized on a cycle-by-cycle basis, thereby imposing much greater preparatory and attentional demands on the central nervous system. To test this hypothesis we used fMRI to measure the BOLD response during syncopation and synchronization to an auditory stimulus. We found that the distribution of cortical and subcortical. areas involved in intentionally coordinating movement with an external metronome depends on the timing pattern employed. Both synchronized and syncopated patterns require activation of contralateral sensorimotor and caudal supplementary motor cortices as well as the (primarily ipsilateral) cerebellum. Moving off the beat, however, requires not only additional activation of the cerebellum but also the recruitment of another network comprised of the basal ganglia, dorsolateral premotor, rostral supplementary motor, prefrontal, and temporal association cortices. No areas were found to be more active during synchronization than. syncopation. The functional role of the cortical and subcortical regions areas involved in syncopation supports the hypothesis that whereas synchronization requires little preparation and monitoring, syncopated movements are planned and executed individually on each perception-action cycle. (C) 2002 Wiley-Liss, Inc.