Using a system-on-a-chip implantable device to filter circulating infected cells in blood or lymph.
Using a system-on-a-chip implantable device to filter circulating infected cells in blood or lymph.
复制标题
使用片上系统植入设备过滤血液或淋巴液中循环的受感染细胞。
DOI：
10.1109/tnb.2003.810160
复制
发表时间：
2003
影响因子：
3.9
通讯作者：
Stryker,GabrielleA
中科院分区：
文献类型：
--
作者：
Hanna,DarrinM;Oakley,BarbaraA;Stryker,GabrielleA
This paper describes a system on a chip (SoC) that makes use of nanoscale cellular adhesion mechanisms in an integrated electronic microsystem to filter infected cells from blood or lymph. An example of a human immunodeficiency virus-specific SoC is explored in depth. Such systems work in vivo, and blood and lymph are filtered on a continuous basis. With the intelligence on the chip, captured cells can be identified and lyzed, expelled, or otherwise acted upon. These types of systems transfer the burden of research from traditional chemotherapy to bioengineering and system design.
