Baseline blood pressure modifies the role of blood pressure variability in mortality: Results from the ACCORD trial.

Baseline blood pressure modifies the role of blood pressure variability in mortality: Results from the ACCORD trial.
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DOI:
10.1111/dom.14649
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发表时间:
2022-05
期刊:
Diabetes, obesity & metabolism
影响因子:
--
通讯作者:
Reaven PD
Reaven PD
中科院分区:
其他
文献类型:
--
作者:
Nuyujukian DS;Newell MS;Zhou JJ;Koska J;Reaven PD

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研究背景既往研究表明,访视间血压变异性(BPV)与平均血压水平无关,与不良心血管结局和死亡率相关。[1-3]这些发现包括有糖尿病和无糖尿病的队列。在最近对2型糖尿病(T2D)患者进行的荟萃分析中,全因死亡率显著增加12%与收缩压相关。[4]美国
BACKGROUNDPrevious studies indicate that visit-to-visit blood pressure variability (BPv), independent of mean blood pressure level, is associated with adverse cardiovascular outcomes and mortality.[1–3] These findings have included cohorts both with and without diabetes. In a recent meta-analysis of patients with type 2 diabetes (T2D), a significant 12% increase in all-cause mortality was linked to systolic BPv.[4]
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