Comparison of whole goat milk and its major fractions regarding the modulation of gut microbiota
Comparison of whole goat milk and its major fractions regarding the modulation of gut microbiota
复制标题
全脂羊奶及其主要成分对肠道微生物群调节的比较
DOI：
10.1002/jsfa.11708
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发表时间：
--
影响因子：
4.1
通讯作者：
Fuxin Zhang
中科院分区：
文献类型：
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作者：
Yufang Liu;Fuxin Zhang
BACKGROUNDGoat milk can be important for human nutrition because of its nutritional value, which may be attributed to its richness in protein, lactose, fat, and other bioactive components. This study compared the diversity and composition of gut microbiota in response to whole goat milk and its major fractions (milk fat, casein, milk whey, whey protein, and whey supernatant). Goat milk, its major fractions, and sterile distilled water (for the control group) were administered to mice intragastrically, and gut microbiota were compared in these groups using metagenomic analysis.RESULTSWe observed distinct patterns of gut microbiota from different diet groups. The sample distance heatmap showed that, compared with other goat milk fractions, gut microbiota in the casein group was more similar to that in the whole goat‐milk group. The relative abundance of the genusLactobacillusincreased significantly after whole goat‐milk treatment; the milk whey fraction increased the abundance ofBlautia; milk fat and milk whey related fractions treatment promoted the population ofBacteroides. The network analysis showed that generaLactobacillusandLactococcuswere negatively associated withHelicobacterandAcinetobacter, respectively.CONCLUSIONFractions of goat milk could contain different gut microbiota from whole goat milk. Consumption of certain goat milk fractions could increase the ingestion of beneficial bacteria and inhibit the growth of some pathogenic bacteria. Our results could provide the basis for the research into and development of goat‐milk based functional foods. © 2021 Society of Chemical Industry.
