Motor control physiology below spinal cord injury: residual volitional control of motor units in paretic and paralyzed muscles.
Motor control physiology below spinal cord injury: residual volitional control of motor units in paretic and paralyzed muscles.
复制标题
脊髓损伤以下的运动控制生理学：麻痹和瘫痪肌肉中运动单位的残余意志控制。
作者：
M. Dimitrijevic;W. McKay;A. Sherwood
我们利用表面多路肌电记录，描述了不同程度脊髓损伤患者在单关节和多关节意志性运动任务中的运动控制。我们已经证明，损伤脊髓的神经生物学状况可以表现为两大类：“新解剖学”和“简化解剖学”。有证据表明，目前或临床上不存在的运动任务的执行中，由意志力引起的运动控制的各种明确特征表明，当我们正在向应用这一新知识恢复人类受损的脊髓功能的过程中，我们可以从动物实验神经生物学研究中受益。关于脊髓损伤后轴突再生能力的成功增强和神经元回路内连通性的改善的报告鼓励我们在研究实验诱导的动物损伤和意外诱导的人类脊髓损伤的恢复过程的同时，加紧努力。
We have described motor control in people with different degrees of SCI by using surface polyelectromyographic recordings during single- and multijoint volitional motor tasks. We have shown that neurobiologic conditions of the injured spinal cord can be expressed in two main categories: "new anatomy" and "reduced anatomy". The evidence for a variety of definite features of motor control elicited by volitional effort for the performance of a present or even clinically absent motor task suggests that we can benefit from animal experimental neurobiologic studies while we are progressing toward the application of this new knowledge for the restoration of impaired spinal cord function in humans. Reports on the successfully enhanced regenerating capabilities of the axons and improved connectivity within neuronal circuits after SCI encourage us to intensify our efforts in parallel with studies on the recovery processes found in experimentally induced lesions in animals, as well as in accidentally induced SCI in humans.