A 2-STEP MECHANISM FOR INTERACTION OF ESTRADIOL WITH RAT UTERUS
A 2-STEP MECHANISM FOR INTERACTION OF ESTRADIOL WITH RAT UTERUS
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DOI：
10.1073/pnas.59.2.632
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发表时间：
1968-01-01
影响因子：
11.1
通讯作者：
DESOMBRE, ER
中科院分区：
文献类型：
--
作者：
JENSEN, EV;SUZUKI, T;DESOMBRE, ER
结果：上清液与核结合的比率：当在体内或体外暴露于氚雌二醇的大鼠子宫在低渗Tris-EDTA中均质时，上清液部分占子宫雌二醇的20%至25%，其中除9.5%S络合物外，不含显著的放射性成分。如果在20℃下进行短暂的雌二醇暴露，
Results.-Ratio of supernatant to nuclearbinding: When rat uteri, previously exposed to tritiated estradiol in vivo or at 370 in vitro, are homogenized in hypotonic Tris-EDTA, the supernatant fraction, which contains no significant radio-active component except 9.5 S complex, represents 20 to 25 per cent of the uterine estradiol. If exposure to estradiol is carried out at 20 for a brief period, the