Elevating sampling.

Elevating sampling.
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提升抽样。

DOI:
10.1039/c4lc00125g
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发表时间:
2014
期刊:
影响因子:
6.1
通讯作者:
Takayama,Shuichi
Takayama,Shuichi
中科院分区:
工程技术1区
文献类型:
--
作者:
Labuz,JosephM;Takayama,Shuichi

文献摘要

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采样-收集、准备和将适当的体积元素(体素)引入系统的过程-在芯片实验室研究中经常被低估并被推到幕后。然而,在可能令人兴奋的技术的原理证明演示与其更广泛的传播和实际使用之间,经常存在的障碍是样品收集和制备的有效性。如果采样效率和可靠性不相同,微流体和纳米流体在改善反应、传感、分离和细胞培养方面的作用就无法发挥。这一视角将突出最近的成功,并评估这一领域当前的挑战和机遇。
Sampling – the process of collecting, preparing, and introducing an appropriate volume element (voxel) into a system – is often underappreciated and pushed behind the scenes in lab-on-a-chip research. What often stands in the way between proof-of-principle demonstrations of potentially exciting technology and its broader dissemination and actual use, however, is the effectiveness of sample collection and preparation. The power of micro- and nanofluidics to improve reactions, sensing, separation, and cell culture cannot be accessed if sampling is not equally efficient and reliable. This perspective will highlight recent successes as well as assess current challenges and opportunities in this area.