Differential Immunodetection of Toxin B from Highly Virulent Clostridium difficile BI/NAP-1/027

Differential Immunodetection of Toxin B from Highly Virulent Clostridium difficile BI/NAP-1/027
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DOI:
10.1128/jcm.03419-14
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发表时间:
2015-05-01
影响因子:
9.4
通讯作者:
Kelly, Ciaran P.
Kelly, Ciaran P.
中科院分区:
医学2区
文献类型:
--
作者:
Pollock, Nira R.;Song, Linan;Kelly, Ciaran P.

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我们开发了一种简单的免疫分析法,能够区分检测粪便中高毒力艰难梭菌菌株(BI/NAP-1/027)的毒素B。该试验可以同时确认体内毒素产生的存在,并提供与感染控制、流行病学和疾病预后相关的菌株相关信息。
We developed a simple immunoassay capable of differentially detecting toxin B from highly virulent strains of Clostridium difficile (BI/NAP-1/027) in stool. This assay can simultaneously confirm the presence of in vivo toxin production and provide strain-related information relevant to infection control epidemiology and disease prognosis.