Interaction between actin and HMM.
Interaction between actin and HMM.
复制标题
肌动蛋白和 HMM 之间的相互作用。
DOI：
10.1016/s0006-291x(86)80207-8
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发表时间：
1986
影响因子：
3.1
通讯作者：
Giordano,M
中科院分区：
文献类型：
--
作者：
Borejdo,J;Giordano,M
结果表明，肌动蛋白和HMM之间的相互作用，在一个快速沉淀acto-HMM凝胶加入MgATP的结果。这简单地证明了肌球蛋白丝的形成不是机械化学反应（肌肉收缩）发生的必要条件，并且可溶性肌球蛋白头能够与肌动蛋白相互作用以产生机械效应。我们的发现也有力地支持了早期的建议，即一个HMM分子的每个头能够与不同的肌动蛋白丝结合。
It is shown that the interaction between actin and HMM results in a rapid precipitaiton of acto-HMM gel upon addition of MgATP. This is a simple demonstration of the idea that the formation of myosin filaments is not essential for mechanochemical reaction (muscle contraction) to occur and that the soluble myosin heads are competent to interact with actin to produce mechanical effect Our findings also strongly support earlier suggestion that each head of one HMM molecule is able to bind to a different actin filament