Three dimensional electron spin resonance (ESR) imaging of internal organs in living mice
Three dimensional electron spin resonance (ESR) imaging of internal organs in living mice
复制标题
活体小鼠内脏三维电子自旋共振 (ESR) 成像
DOI：
10.1080/15216549800204242
复制
发表时间：
1998
期刊：
影响因子：
4.6
通讯作者：
L. Packer
中科院分区：
文献类型：
--
作者：
T. Masumizu;K. Fujii;M. Kohno;Soichi Nagai;Yuji Odagaki;Mamoru Imanari;Akitane Mori;L. Packer
在VIVA中，对口服氮氧化物自由基自旋探针后的活小鼠进行了电子自旋共振成像(ESR成像)。为了获得自旋探针在活体动物体内的准确分布，在活体内应用了3D ESR成像程序。成像图像显示，给药的自旋探针首先位于胃内，然后被输送到动物的肝脏、肾脏和心脏。
In viva electron spin resonance imaging (ESR imaging) was applied to living mice after peroral administration of a nitroxide radical spin probe. A 3D ESR imaging procedure was applied in vivo in order to obtain the exact distribution of the spin probe in a living animal. The imaging pictures demonstrated that the administered spin probe was firstly located in the stomach, then delivered to the liver, kidney and heart of the animal.