A CRITICAL-APPRAISAL OF THE RESEARCH LITERATURE INVESTIGATING FATIGUE IN THE INDIVIDUAL WITH CANCER
A CRITICAL-APPRAISAL OF THE RESEARCH LITERATURE INVESTIGATING FATIGUE IN THE INDIVIDUAL WITH CANCER
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DOI：
10.1097/00002820-199114040-00004
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发表时间：
1991-08-01
期刊：
影响因子：
2.6
通讯作者：
GRAYDON, J
中科院分区：
文献类型：
--
作者：
IRVINE, DM;VINCENT, L;GRAYDON, J
疲劳是一种常见的症状，它可能是几乎任何疾病的组成部分，也可能是心理、身体或混合原因造成的。护士需要了解疲劳的发生、持续和发展，以便成功地干预癌症患者，使其适应诊断和治疗。虽然文献是重要的信息来源，但在根据研究结果制定实践指南之前，必须对研究结果进行批判性的解释。对研究癌症患者疲劳问题的研究文献进行了批判性评价。有强有力的证据表明，在接受化疗和放疗的癌症患者中，疲劳是一个普遍存在的问题。然而，过去的研究一直受到方法论问题的限制。通常，研究没有包括对照组，没有对可能的混杂变量进行控制，并且将测量限制在可靠性和有效性有限的一维尺度上。虽然已经假设了疲劳的几个相关因素，但到目前为止，研究还没有发现体重减轻、贫血或心理困扰等相关因素之间的一致关系。这篇文章回顾了目前对癌症患者疲劳的了解，以及如何设计未来的研究来改进过去的测量和采样问题。
Fatigue is a commonly experienced symptom, which may be a component of virtually any disease and can have a psychological, physical, or mixed origin. Nurses need to understand the onset, duration, and progression of fatigue to intervene successfully with the cancer patient adapting to diagnosis and treatment. While the literature is an important source of information, results of research studies must be critically interpreted before proceeding with practice guidelines based on research findings. A critical appraisal of the research literature investigating the problem of fatigue in individuals with cancer was conducted. There is strong evidence to suggest that fatigue is a prevalent problem among cancer patients receiving chemotherapy and radiation therapy. However past research has been limited by methodological problems. Typically, studies fail to include a control group, do not control for possible confounding variables, and have restricted measurement to unidimensional scales with limited reliability and validity. While several correlates of fatigue have been postulated, research to date has found no consistent relationships among such correlates as weight loss, anemia, or psychological distress. This article reviews what is currently known about fatigue in the cancer patient and how future research could be designed to improve on past measurement and sampling problems.