Correlation Between Magnetic Resonance Imaging and Clinical Outcomes After Cartilage Repair Surgery in the Knee
Correlation Between Magnetic Resonance Imaging and Clinical Outcomes After Cartilage Repair Surgery in the Knee
复制标题
磁共振成像与膝关节软骨修复手术后临床结果的相关性
DOI：
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发表时间：
2013
影响因子：
4.8
通讯作者：
R. Brophy
中科院分区：
文献类型：
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作者：
A. Blackman;Matthew V. Smith;D. Flanigan;M. Matava;R. Wright;R. Brophy
背景：磁共振成像（MRI）常用于评估手术修复后的软骨。MRI与临床结果之间的相关性尚不清楚。假设：术后MRI结果与膝关节软骨手术患者的临床结果相关。研究设计：荟萃分析。方法：对文献进行系统回顾，以确定自体软骨细胞植入（ACI）、自体骨软骨移植系统（OATS）或微骨折后MRI和临床结果相关的研究。研究报告了不同MRI参数的相关系数(r)，然后纳入meta分析。结果：本系统综述共纳入26项研究，其中15项纳入meta分析。大多数研究（n = 19）涉及ACI，尽管有关于OATS （n = 5）和微骨折（n = 4）的研究。ACI后MRI与临床预后相关性最强的是移植物肥厚（r = 0.72）和修复组织信号（r = 0.71）。微骨折后MRI相关性最强的是Henderson评分（r = 0.97）、软骨下水肿（r = 0.77）和修复组织信号（r = 0.76）。燕麦后相关性不强，缺陷填充（r = 0.53）和修复组织结构（r = 0.51）最强。结论：MRI结果确实与膝关节软骨修复手术后的临床结果相关，尽管相关的具体参数因手术类型而异。目前尚无MRI分类系统与所有类型软骨修复手术后的临床结果相关。
Background: Magnetic resonance imaging (MRI) is often used to assess cartilage after surgical repair. The correlation between MRI and clinical outcomes is not well understood. Hypothesis: Postoperative MRI findings correlate with clinical outcome measures in patients after articular cartilage surgery of the knee. Study Design: Meta-analysis. Methods: A systematic review of the literature was performed to identify studies in which MRI and clinical outcomes were correlated after autologous chondrocyte implantation (ACI), osteochondral autograft transfer system (OATS), or microfracture. Studies that reported correlation coefficients (r) for different MRI parameters were then included in a meta-analysis. Results: A total of 26 studies were identified for inclusion in this systematic review, 15 of which were included in the meta-analysis. Most of the studies (n = 19) involved ACI, although studies were available for OATS (n = 5) and microfracture (n = 4). The strongest MRI correlates with clinical outcomes after ACI were graft hypertrophy (r = 0.72) and repair tissue signal (r = 0.71). After microfracture, the strongest MRI correlates were the Henderson score (r = 0.97), subchondral edema (r = 0.77), and repair tissue signal (r = 0.76). Correlations after OATS were not as strong, with defect fill (r = 0.53) and repair tissue structure (r = 0.51) being the strongest. Conclusion: The MRI findings do correlate with clinical outcomes after cartilage repair surgery in the knee, although the specific parameters that correlate best vary by the type of procedure performed. No current MRI classification system has been shown to correlate with clinical outcomes after all types of cartilage repair surgery.
膝关节软骨修复的磁共振成像。
DOI：
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发表时间：
1998
期刊：
Topics in magnetic resonance imaging : TMRI.
影响因子：
--
作者：
Gold,GE;Bergman,AG;Pauly,JM;Lang,P;Butts,RK;Beaulieu,CF;Hargreaves,B;Frank,L;Boutin,RD;Macovski,A;Resnick,D
通讯作者：
Resnick,D