Hemodynamics of Mechanical Circulatory Support
Hemodynamics of Mechanical Circulatory Support
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DOI：
10.1016/j.jacc.2015.10.017
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发表时间：
2015-12-15
影响因子：
24
通讯作者：
Uriel, Nir
中科院分区：
文献类型：
--
作者：
Burkhoff, Daniel;Sayer, Gabriel;Uriel, Nir
越来越多的器械可为急性血流动力学受损和慢性终末期心力衰竭患者提供机械循环支持（MCS）。这些装置通过不同的泵送机构工作，具有不同的流动能力，通过不同的技术插入，并且具有血液从其抽出并返回到身体的不同部位。这些因素导致不同的主要血流动力学效应和身体的次要反应。然而，在为特定患者选择器械或管理接受MCS的患者时，通常不会考虑这些因素。在这篇综述中，我们讨论了心脏、血管和泵力学的基本原理，并说明了它们如何为理解心脏、血管系统和器械之间的复杂相互作用提供广泛的基础，以及它们如何有助于指导未来的研究以改善患者的预后。(C)2015年由美国心脏病学会基金会。
An increasing number of devices can provide mechanical circulatory support (MCS) to patients with acute hemodynamic compromise and chronic end-stage heart failure. These devices work by different pumping mechanisms, have various flow capacities, are inserted by different techniques, and have different sites from which blood is withdrawn and returned to the body. These factors result in different primary hemodynamic effects and secondary responses of the body. However, these are not generally taken into account when choosing a device for a particular patient or while managing a patient undergoing MCS. In this review, we discuss fundamental principles of cardiac, vascular, and pump mechanics and illustrate how they provide a broad foundation for understanding the complex interactions between the heart, vasculature, and device, and how they may help guide future research to improve patient outcomes. (C) 2015 by the American College of Cardiology Foundation.