Laterality of motor cortical function measured by transcranial magnetic stimulation threshold tracking.
Laterality of motor cortical function measured by transcranial magnetic stimulation threshold tracking.
复制标题
通过颅磁刺激阈值跟踪测量运动皮质功能的偏侧性。
DOI：
10.1002/mus.25372
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Kiernan MC.
中科院分区：
文献类型：
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作者：
Shibuya K;Park SB;Howells J;Huynh W;Noto YI;Shahrizaila N;Matamala JM;Vucic S;Kiernan MC.
简介：阈值跟踪配对脉冲经颅磁刺激（TTTMS）检查皮质功能，可用于诊断运动神经元疾病。已经使用恒定刺激方法确定了优势和非优势肢体之间的皮质功能差异，但这些差异仍不清楚，可能是由于方法学差异。在这项研究中，我们的目的是澄清优势和非优势肢体之间的皮层功能的差异使用TTTMS.方法：单脉冲TMS，TTTMS，和神经传导研究进行了25名健康，右利手参与者从拇短展肌记录。结果：在静息运动阈值、运动诱发电位（MEP）振幅、MEP潜伏期、中枢运动传导时间、皮质静默期、短间期皮质内抑制和易化、复合肌肉动作电位（CMAP）振幅、CMAP潜伏期、F波潜伏期或神经生理学指标。结论：这些结果表明，当使用TTTMS时，优势半球和非优势半球之间的皮质功能没有差异。424-427，2017年
Introduction: Threshold tracking paired‐pulse transcranial magnetic stimulation (TTTMS) examines cortical function and is useful for diagnosis of motor neuron disorders. Differences in cortical function have been identified between dominant and non‐dominant limbs using constant stimulus methods, but they remain unclear, potentially due to methodological differences. In this study we aimed to clarify differences in cortical function between dominant and non‐dominant limbs using TTTMS.Methods: Single‐pulse TMS, TTTMS, and nerve conduction studies were performed in 25 healthy, right‐handed participants by recording from the abductor pollicis brevis muscle.Results: There were no side‐to‐side differences observed in resting motor threshold, motor evoked potential (MEP) amplitude, MEP latency, central motor conduction time, cortical silent period, short‐interval intracortical inhibition and facilitation, compound muscle action potential (CMAP) amplitude, CMAP latency, F‐wave latency, or neurophysiological index.Conclusions: These findings suggest that, when using TTTMS, there are no differences in cortical function between dominant and non‐dominant hemispheres.Muscle Nerve55: 424–427, 2017