Refractive error and biometrics of anterior segment of eyes of healthy young university students in Japan
Refractive error and biometrics of anterior segment of eyes of healthy young university students in Japan
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DOI：
10.1038/s41598-019-51920-4
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发表时间：
2019-10-25
影响因子：
4.6
通讯作者：
Hirano, Koji
中科院分区：
文献类型：
--
作者：
Kato, Kumiko;Kondo, Mineo;Hirano, Koji
确定与健康年轻日本大学生屈光不正显着相关的眼前节参数。这是一项横断面观察研究，对象为 229 名年龄在 20 至 29 岁之间的健康日本大学生（男性：女性，147：82）。进行单变量和多元线性回归分析以确定与屈光不正显着相关的因素。自变量包括年龄、性别、眼轴长度、前房深度、角膜直径、角膜前表面曲率和中央角膜厚度。平均屈光不正（等效球镜）为-4.1 +/- 2.7 屈光度 (D)，范围为 -12.5 至 +0.5 D，平均眼轴长度为 25.4 +/- 1.3 mm，范围为 22.4 至 29.0 mm。 Pearson单变量相关分析发现，屈光不正与眼轴长度（R = -0.82，P < 0.001）、前房较深（R = -0.30，P < 0.001）和角膜直径较大（R = -0.21，P = 0.001）呈显着负相关。多元回归分析显示，屈光不正与较长的眼轴长度（P < 0.001）、较深的前房（P < 0.001）和较平坦的角膜曲率（P < 0.001）显着相关。眼前节的生物特征值应该使眼睛更加远视，这将减少近视引起的眼轴长度的延长。
To determine the parameters of the anterior segment of eyes that are significantly associated with the refractive error in healthy young Japanese university students. This was a cross-sectional observational study of 229 healthy Japanese university students (men: women,147:82) whose age ranged between 20 to 29 years. Univariate and multivariate linear regression analyses were performed to identify the factors that were significantly correlated with the refractive error. The independent variables included age, sex, axial length, anterior chamber depth, corneal diameter, curvature of anterior surface of cornea, and central corneal thickness. The mean refractive error (spherical equivalent) was -4.1 +/- 2.7 diopters (D) with a range of -12.5 to +0.5 D, and the mean axial length was 25.4 +/- 1.3 mm with a range of 22.4 to 29.0 mm. Pearson univariate correlation analysis found that the refractive error was significantly and negatively correlated with the axial length (R = -0.82, P < 0.001), deeper anterior chamber (R = -0.30, P < 0.001), and larger corneal diameter (R = -0.21, P = 0.001). Multiple regression analysis showed that the refractive error was significantly associated with a longer axial length (P < 0.001), a deeper anterior chamber (P < 0.001), and a flatter corneal curvature (P < 0.001). The biometric values of the anterior segment of the eyes should make the eye more hyperopic which would reduce the myopia-inducing lengthening of the axial length.