Analysis of brominated and chlorinated flame retardants, organophosphate esters, and polycyclic aromatic hydrocarbons in silicone wristbands used as personal passive samplers.
Analysis of brominated and chlorinated flame retardants, organophosphate esters, and polycyclic aromatic hydrocarbons in silicone wristbands used as personal passive samplers.
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分析用作个人被动采样器的硅胶腕带中的溴化和氯化阻燃剂、有机磷酸酯和多环芳烃。
DOI：
10.1016/j.chroma.2018.12.041
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Salamova,Amina
中科院分区：
文献类型：
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作者：
Romanak,KevinA;Wang,Shaorui;Stubbings,WilliamA;Hendryx,Michael;Venier,Marta;Salamova,Amina
我们首次提出了一种分析方法，同时提取，分馏和量化硅胶腕带中的四组半挥发性有机化合物（SVOCs），包括35多溴联苯醚（PBDEs），10种新型阻燃剂（NFRs），19种有机磷酸酯（OPEs）和13种多环芳烃（PAH）。使用超声波提取腕带，并在两个多层柱上进行清洁和分馏：一个由中性氧化铝、中性二氧化硅和Florisil组成，另一个由中性氧化铝、中性二氧化硅和酸性二氧化硅组成。使用加标腕带样品（n = 8）和程序空白（n = 7）验证方法准确度和精密度。所有目标分析物的平均基质加标回收率百分比在57-107%范围内，相对标准误差<20%，少数例外。该方法被应用于分析10名参与者佩戴7天的13个腕带; 3名参与者佩戴两个腕带以评估重复样品。这些腕带中所有四组分析物的替代标准品的回收率均在80-120%范围内，只有少数例外：13 C12 BDE-209和13 C12-磷酸三苯酯的回收率分别为35 - 62%和69- 176%。在至少一半的佩戴腕带中检测到大多数目标分析物。在已部署的腕带中，多溴二苯醚、NFR、OPEs和PAH的总含量分别为28.4至412纳克、40.7至625纳克、2440至9580纳克和76.2至1240纳克。
For the first time, we present an analytical method to simultaneously extract, fractionate, and quantify four groups of semi-volatile organic compounds (SVOCs) in silicone wristbands, including 35 polybrominated diphenyl ethers (PBDEs), 10 novel flame retardants (NFRs), 19 organophosphate esters (OPEs), and 13 polycyclic aromatic hydrocarbons (PAHs). Wristbands were extracted using ultrasonication, and cleaned and fractionated on two multi-layer columns: one consisting of neutral alumina, neutral silica and Florisil, and the other consisting of neutral alumina, neutral silica, and acidic silica. Method accuracy and precision were validated using spiked wristband samples (n = 8) and procedural blanks (n = 7). Average matrix spike percent recoveries for all target analytes were within 57–107% with relative standard errors < 20%, with a few exceptions. This method was applied to analyze thirteen wristbands worn by ten participants for seven days; three participants wore two wristbands to evaluate duplicate samples. Percent recoveries of surrogate standards for all four groups of analytes in these wristbands were all within the 80–120% range with a few exceptions: recoveries for13C12BDE-209 and for13C12-triphenyl phosphate ranged from 35 to 62% and 69–176%, respectively. The majority of target analytes were detected in at least half of worn wristbands. The levels of total PBDEs, NFRs, OPEs and PAHs in deployed wristbands ranged from 28.4 to 412 ng, 40.7 to 625 ng, 2440 to 9580 ng, and 76.2 to 1240 ng, respectively.