Large dsDNA chloroviruses encode diverse membrane transport proteins.
Large dsDNA chloroviruses encode diverse membrane transport proteins.
复制标题
DOI：
10.1016/j.virol.2015.02.025
复制
发表时间：
2015-05
期刊：
影响因子：
3.7
通讯作者：
G. Thiel;T. Greiner;D. Dunigan;A. Moroni;J. V. Van Etten
中科院分区：
文献类型：
--
作者：
G. Thiel;T. Greiner;D. Dunigan;A. Moroni;J. V. Van Etten
许多感染某些小球藻样绿藻(氯病毒)分离株的大型DNA病毒是不寻常的，因为它们通常编码一系列不同的膜运输蛋白，包括功能K+通道和水甘油疏松蛋白以及K+转运和钙转运ATPase。一些氯病毒还编码可能的配基门控类通道蛋白。所有已测序的氯病毒中不存在一种蛋白质，但K+通道是最常见的，因为只分离出两种缺乏这种完整蛋白质的氯病毒。这篇综述描述了这些膜转运蛋白的性质，并提出了其中一些可能的生理功能和进化史。
Many large DNA viruses that infect certain isolates of chlorella-like green algae (chloroviruses) are unusual because they often encode a diverse set of membrane transport proteins, including functional K+channels and aquaglyceroporins as well as K+transporters and calcium transporting ATPases. Some chloroviruses also encode putative ligand-gated-like channel proteins. No one protein is present in all of the chloroviruses that have been sequenced, but the K+channel is the most common as only two chloroviruses have been isolated that lack this complete protein. This review describes the properties of these membrane-transporting proteins and suggests possible physiological functions and evolutionary histories for some of them.