Gender-specific effect of pregnancy-related anxiety on preschooler's emotional and behavioral development: A population-based cohort study
Gender-specific effect of pregnancy-related anxiety on preschooler's emotional and behavioral development: A population-based cohort study
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怀孕相关焦虑对学龄前儿童情绪和行为发展的性别特异性影响：一项基于人群的队列研究
DOI：
10.1016/j.jad.2020.10.014
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发表时间：
2021
影响因子：
6.6
通讯作者：
Huang Kun
中科院分区：
文献类型：
--
作者：
Wang Xiaoxu;Xie Jingjing;Wu Ya;Wu Xiaoyan;Yan Shuangqin;Xu Yeqing;Zhu Peng;Hao Jiahu;Tao Fangbiao;Huang Kun
背景妊娠相关焦虑对后代的神经发育有重要影响。然而，它对儿童情绪和行为发展的性别特异性影响存在争议，关键期的知识有限。本研究旨在探讨不同性别的孕妇焦虑对学龄前儿童情绪和行为发展的影响。最终数据分析共纳入3443对母子。分别于妊娠1、3个月采用妊娠相关焦虑问卷对孕妇的妊娠相关焦虑进行评定。由父母完成优势和困难量表（SDQ），以评估学龄前男孩和女孩的情感和行为发展。Logistic回归模型被用来研究怀孕相关的焦虑和学龄前儿童的情绪和行为problems.ResultsThe怀孕相关的焦虑的总体患病率为31.6%之间的关联。与母亲在孕早期和孕晚期均无妊娠相关焦虑的儿童相比，母亲在孕早期和孕晚期有妊娠相关焦虑的儿童所生的学龄前男孩有更高的行为问题风险。孕早期、孕晚期和孕中期的妊娠焦虑均与学龄前男孩的多动和总的困难问题有关。妊娠相关焦虑在孕早期和两个1stand 3rdtrimester增加学龄前女孩的情绪问题和总的困难problems.ConclusionPregnancy相关焦虑可能与学龄前男孩的外化问题在早期和晚期的怀孕和增加的风险内化问题的女孩在早期pregnancy.LimitationsThere是没有数据妊娠相关焦虑在孕中期。
BackgroundPregnancy-related anxiety plays a major role in shaping offspring's neural development. However, its gender-specific effect on children's emotional and behavioral development is controversial and the knowledge of critical period is limited. This study aims to examine gender-specific effect of pregnancy-related anxiety on preschooler's emotional and behavioral development.MethodsThis study was based on the China-Anhui Birth Cohort Study (C-ABCS). A total of 3443 mother-child pairs were included in final data analysis. Pregnancy-related anxiety was assessed by Pregnancy-Related Anxiety Questionnaire respectively in the 1stand 3rdtrimester of pregnancy. Strengths and Difficulties Questionnaires (SDQ) were completed by parents to assess preschool emotional and behavioral development in boys and girls. Logistic regression models were used to examine the association between pregnancy-related anxiety and preschoolers’ emotional and behavioral problems.ResultsThe overall prevalence of pregnancy-related anxiety was 31.6%. Compared with those whose mothers without pregnancy-related anxiety in either 1stor 3rdtrimester, preschool boys born of mothers with pregnancy-related anxiety in the 1sttrimester and in the 3rdtrimester had an increased risk of conduct problems. Pregnancy-related anxiety in the 1st, 3rdtrimester and in both trimesters all related with preschool boys’ hyperactivity and total difficult problems. Pregnancy-related anxiety in the 1sttrimester and in both 1stand 3rdtrimester increased the risk of preschool girls’ emotional problems and total difficult problems.ConclusionPregnancy-related anxiety may relate with preschool boys’ externalizing problems in early and late of pregnancy and increase the risk of internalizing problems in girls in early pregnancy.LimitationsThere was no data on pregnancy-related anxiety in the second trimester.