WFS1-deficiency enhances endoplasmic reticulum stress, triggers apoptotic pathway and impairs cell cycle progression specifically in pancreatic β-cells.
WFS1-deficiency enhances endoplasmic reticulum stress, triggers apoptotic pathway and impairs cell cycle progression specifically in pancreatic β-cells.
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WFS1 缺陷会增强内质网应激,触发细胞凋亡途径并损害细胞周期进程,特别是在胰腺 β 细胞中。
DOI:
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发表时间:
2006
期刊:
影响因子:
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通讯作者:
Oka Y
中科院分区:
文献类型:
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作者:
Yamada T;Ishihara H;Tamura A;Takahashi R;Yamaguchi S;Takei D;Tokita A;Satake C;Tashiro F;Katagiri H;Aburatani H;Miyazaki J-I;Oka Y