Response reversal and children with psychopathic tendencies: success is a function of salience of contingency change

Response reversal and children with psychopathic tendencies: success is a function of salience of contingency change
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DOI:
10.1111/j.1469-7610.2004.00398.x
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发表时间:
2005-09-01
影响因子:
7.6
通讯作者:
Blair, RJR
Blair, RJR
中科院分区:
医学1区
文献类型:
--
作者:
Budhani, S;Blair, RJR

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背景:以前的工作并不一致地报道了有精神病倾向的儿童在反应逆转/消退方面的困难。方法:我们检验了这样一个假设,即在有精神病倾向的儿童中看到的损害程度是偶然变化的显著性的函数。我们调查了有精神病倾向的儿童在一项新的概率反应逆转任务中的表现,该任务涉及四种具有分级奖惩偶然性的条件(100-0,90-10,80-20和70-30;即,对于100-0偶然事件,响应一个对象总是被奖励,而响应另一个对象总是被惩罚)。实验结果:与预测一致,在有精神病倾向的儿童中观察到的损害是应急变化显著性的反函数。结论:我们认为,这一数据是一致的建议微妙的眶额叶皮层损伤的儿童精神病倾向。
Background: Previous work has inconsistently reported difficulties with response reversal/extinction in children with psychopathic tendencies. Method: We tested the hypothesis that the degree of impairment seen in children with psychopathic tendencies is a function of the salience of contingency change. We investigated the performance of children with psychopathic tendencies on a novel probabilistic response reversal task involving four conditions with gradated reward-punishment contingencies (100-0, 90-10, 80-20 and 70-30; i.e., for the 100-0 contingency, responding to one object is always rewarded while responding to the other is always punished). results: In line with predictions, the impairment seen in the children with psychopathic tendencies was an inverse function of the salience of the contingency change. Conclusions: We suggest that this data is consistent with suggestions of subtle orbital frontal cortex impairment in children with psychopathic tendencies.